Fig. 7
From: Molecular mechanism of anti-cancer activity of phycocyanin in triple-negative breast cancer cells
Phycocyanin inhibits vascular channel formation in MDA MB 231 cells (a) Representative phase contrast images of vascular channels monitored through 0–10 h following treatment with 3 μm PC. Inhibition of vascular channel formation was evident in as early as 6 h indicating potent anti-angiogenic effects (b) qPCR analysis for VEGFR2 and MMP-9 genes in MDA MB 231 cells treated with 3 μM or without PC for 24 h. (# P = 0.064, ***P < 0.0001 compared with untreated controls)