Table 1 Patient characteristics and TNIK expression in stage I-III CRC patients

Age

< 70 years

98

53

0.435

≥ 70 years

41

28

Gender

male

88

60

0.102

female

51

21

Histology (TNM 7th)

G1

62

28

0.258

G2

70

46

G3

7

7

Tumor location

right-sided colon

26

28

0.016

left-sided colon

58

22

rectum

55

31

Stage (TNM 7th)

I

36

12

0.104

II

55

32

III

48

37

Depth of tumor invasion (TNM 7th)

T1

17

6

T1-3 vs. T4 0.002

T2

32

11

T3

58

29

T4

32

35

Lymphatic invasion

(-)

50

17

0.021

(+)

89

64

Venous invasion

(-)

27

6

0.020

(+)

112

75

Lymph node metastasis

(-)

91

44

0.102

(+)

48

37

CEA*¹

< 5 ng/ml

101

52

0.189

≥ 5 ng/ml

38

29

Distant recurrence

(-)

118

49

< 0.001

(+)

21

32