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Table 1 Characteristics of the PDAC patients included in the study

From: Circulating tumor cells (CTC) and KRAS mutant circulating free DNA (cfDNA) detection in peripheral blood as biomarkers in patients diagnosed with exocrine pancreatic cancer

Patient Code Disease Stage QT before CTC/KRAS cfDNA determination KRAS cfDNA data CTC data CTC/KRAS cfDNA data DNA concentration in plamsa (Average copies RNaseP/20ul plasma) KRAS status in plasma KRAS Mutation in plasma Ratio M:WT KRAS in plasma CTC STATUS Number of CTC CD45 Depletion KRAS mutation Mutation in Tissue
1 R YES YES    80 NEG       G12D
2 R YES YES    43 NEG       G12R
3 R YES YES    59 NEG       
4 R NO YES YES YES 106 NEG    NEG 0   
5 R NO YES YES YES 97 NEG    NEG 0 WT WT
6 R NO YES YES YES 185 POS G12D 0,21 POS 1   G12D
7 R NO   YES       NEG 0 WT  
8 R NO   YES       NEG 0   
9 R NO YES    86 POS G12D 0,1    WT WT
10 R NO YES YES YES 93 POS G12D 0,01 NEG 0   G12D
11 R NO YES YES YES 48 NEG    NEG 0   G12S
12 R NO YES YES YES 1541 NEG    NEG 0   
13 R NO   YES       NEG 0   
14 R NO   YES       NEG 0   
15 LA NO YES    52 POS G12V 0,12     
16 LA NO YES YES yes 6,4 NEG    NEG 0   
17 LA NO YES YES YES 66 NEG    NEG 0 G12D  
18 LA NO YES YES YES 1063 NEG    NEG 0   
19 LA NO   YES       NEG 0   
20 LA YES YES    297 NEG       
21 LA NO YES YES YES 700 NEG    NEG 0   
22 LA YES YES YES YES 38 NEG    NEG 0   
23 LA NO YES YES YES 111 NEG    NEG 0   
24 LA NO   YES       NEG 0   
25 LA NO   YES       NEG 0 G12D  
26 LA NO   YES       NEG 0   
27 LA NO   YES       NEG 0   
28 M NO YES    806 POS G12D 0,06     
29 M NO YES YES YES 12,2 NEG    NEG 0   
30 M YES YES YES YES 1663 POS G12D 2,43 POS 5   WT
31 M NO YES YES YES 72 NEG    NEG 0   WT
32 M NO YES YES YES 1095 POS G12R 0,02 POS 4   G12R
33 M NO   YES       NEG 0   
34 M NO   YES       NEG 0   
35 M NO   YES       POS 3   
36 M NO YES    130 NEG       
37 M NO YES    147 NEG      G12D  
38 M YES YES    87 NEG       G12D
39 M NO YES YES YES 33 NEG    NEG 0   WT
40 M NO YES YES YES 328 NEG    NEG 0 G12D  
41 M NO YES YES YES 602 POS G12D 0,81 POS 3   
42 M NO YES YES YES 70 NEG    NEG 0 WT  
43 M NO YES YES YES 52 NEG    POS 1 WT  
44 M NO   YES       NEG 0   
45 M NO   YES       POS 13   
  1. R Resectable, LA Locally Advanced, M Metastatic