Fig. 2

p38 MAPK and p-p38 MAPK expressions in non-responders DLBCL patients. a p38 MAPK expression according to the clinical response. P38 MAPK expression was assessed by IHC in 80 biopsies. The % expression was calculated from the TMA p38 MAPK staining. Black lines represent the medians, whiskers marking the lower and upper adjacent values. b p-p38 MAPK expression in responder (R) and non-responder (NR) patients. The % of tumor samples expressing p-p38 was determined from the TMA staining of p-p38 MAPK. c There is a significant expression of p-p38 MAPK in the NR. The % of p-p38 MAPK expression was determined in TMA and the % threshold (30) was defined by the ROC curves and by the Younden index to separate the % depending on the response to treatment