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Table 4 Toxicity during induction chemotherapy according to CTCAE 4.0 (76 evaluable patients) by genotype (% per group)

From: CYP39A1 polymorphism is associated with toxicity during intensive induction chemotherapy in patients with advanced head and neck cancer

 

Genotype rs7761731

Total population (n = 76)

AA (n = 33

AT (n = 36)

TT (n = 8)

Leucopenia G3/4 (%)

65.6 %

45.7 %

37.5 %

52.6 %

Infection G3/4 (%)

40.6 %

20.0 %

25.0 %

28.9 %

Renal Toxicity > G1 (%)

6.3 %

14.3 %

12.5 %

11.8 %

Thrombopenia G3 (%)

na.

2.8

na.

1.3 %

  1. na. not available
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BMC Cancer

ISSN: 1471-2407

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