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Table 1 Demographics

From: Prior oral contraceptive use in ovarian cancer patients: assessing associations with overall and progression-free survival

Characteristic

Oral contraceptive usea

P-valueb

 

Never-Used

Ever-Used

Total

 

n = 571

n = 827

n = 1398

 

(%)

(%)

(%)

 

Age at diagnosis, median in years (range)

69 (24, 93)

58 (21, 91)

61 (21, 93)

<0.0001

Cancer stage

    

 1

77 (14)

149 (19)

226 (17)

0.07

 2

34 (6)

44 (6)

78 (6)

 

 3

322 (60)

460 (59)

782 (60)

 

 4

106 (20)

124 (16)

230 (17)

 

Tumor Type

    

 High-grade serous

320 (56)

419 (51)

739 (53)

0.09

 Endometrioid

71 (12)

91 (11)

162 (12)

 

 Clear cell

32 (6)

46 (6)

78 (6)

 

 Mucinous

9 (2)

23 (3)

32 (2)

 

 Other

139 (24)

147 (29)

387 (27)

 

Grade

    

 1

22 (5)

49 (8)

71 (7)

0.06

 2

45 (10)

77 (12)

122 (11)

 

 3

260 (58)

362 (58)

622 (58)

 

 4

123 (27)

140 (22)

263 (24)

 

Tumor Debulking Status

    

 No residual disease

218 (39)

393 (48)

611 (45)

0.004

 Less than or equal to 1 centimeter

150 (27)

172 (21)

322 (24)

 

 Optimal but amount of residual disease unknown

79 (14)

105 (13)

184 (13)

 

 Suboptimal

79 (14)

86 (11)

165 (12)

 

 Unknown

33 (6)

57 (7)

90 (7)

 

Platinum-based chemotherapy within 3 months of surgery

    

 Yes

309 (87)

530 (93)

839 (90)

0.002

 No

48 (13)

42 (7)

90 (10)

 

Age at menarche, median in years (range)

13 (9, 19)

13 (8, 19)

13 (8, 19)

0.19

Age at menopause, median in years (range)

50 (18, 76)

50 (21, 60)

50 (18, 76)

0.26

Number of live births

    

 0

113 (20)

139 (17)

252 (18)

<0.0001

 1-2

177 (31)

374 (45)

551 (40)

 

 3 or more

278 (49)

313 (38)

591 (42)

 

Smoking

    

 Never

342 (66)

480 (62)

822 (64)

0.25

 Former

136 (26)

234 (30)

370 (29)

 

 current

38 (7)

63 (8)

101 (8)

 

Breast or ovarian cancer in a first-degree relative

    

 Yes

133 (24)

188 (23)

321 (23)

0.75

 No

426 (76)

628 (77)

1054 (77)

 
  1. aNumbers may not sum to the whole cohort or to 100 % either because of missing values or rounding, and numbers in parentheses represent percentages unless otherwise specified
  2. bChi square or Wilcoxon rank-sum test were used to compare Never- and Ever-Users, as appropriate