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Table 1 Demographics

From: Prior oral contraceptive use in ovarian cancer patients: assessing associations with overall and progression-free survival

Characteristic Oral contraceptive usea P-valueb
  Never-Used Ever-Used Total  
n = 571 n = 827 n = 1398  
(%) (%) (%)  
Age at diagnosis, median in years (range) 69 (24, 93) 58 (21, 91) 61 (21, 93) <0.0001
Cancer stage     
 1 77 (14) 149 (19) 226 (17) 0.07
 2 34 (6) 44 (6) 78 (6)  
 3 322 (60) 460 (59) 782 (60)  
 4 106 (20) 124 (16) 230 (17)  
Tumor Type     
 High-grade serous 320 (56) 419 (51) 739 (53) 0.09
 Endometrioid 71 (12) 91 (11) 162 (12)  
 Clear cell 32 (6) 46 (6) 78 (6)  
 Mucinous 9 (2) 23 (3) 32 (2)  
 Other 139 (24) 147 (29) 387 (27)  
Grade     
 1 22 (5) 49 (8) 71 (7) 0.06
 2 45 (10) 77 (12) 122 (11)  
 3 260 (58) 362 (58) 622 (58)  
 4 123 (27) 140 (22) 263 (24)  
Tumor Debulking Status     
 No residual disease 218 (39) 393 (48) 611 (45) 0.004
 Less than or equal to 1 centimeter 150 (27) 172 (21) 322 (24)  
 Optimal but amount of residual disease unknown 79 (14) 105 (13) 184 (13)  
 Suboptimal 79 (14) 86 (11) 165 (12)  
 Unknown 33 (6) 57 (7) 90 (7)  
Platinum-based chemotherapy within 3 months of surgery     
 Yes 309 (87) 530 (93) 839 (90) 0.002
 No 48 (13) 42 (7) 90 (10)  
Age at menarche, median in years (range) 13 (9, 19) 13 (8, 19) 13 (8, 19) 0.19
Age at menopause, median in years (range) 50 (18, 76) 50 (21, 60) 50 (18, 76) 0.26
Number of live births     
 0 113 (20) 139 (17) 252 (18) <0.0001
 1-2 177 (31) 374 (45) 551 (40)  
 3 or more 278 (49) 313 (38) 591 (42)  
Smoking     
 Never 342 (66) 480 (62) 822 (64) 0.25
 Former 136 (26) 234 (30) 370 (29)  
 current 38 (7) 63 (8) 101 (8)  
Breast or ovarian cancer in a first-degree relative     
 Yes 133 (24) 188 (23) 321 (23) 0.75
 No 426 (76) 628 (77) 1054 (77)  
  1. aNumbers may not sum to the whole cohort or to 100 % either because of missing values or rounding, and numbers in parentheses represent percentages unless otherwise specified
  2. bChi square or Wilcoxon rank-sum test were used to compare Never- and Ever-Users, as appropriate