| |
Controls (n = 136)
|
Unilateral cases (n = 165)
|
Bilateral cases (n = 87)
|
|---|
| | |
Crudea
|
Adjustedb
| |
Crudea
|
Adjustedb
|
|---|
|
Medical conditions
|
N (%)
|
N (%)
|
OR
|
OR (95 % CI)
|
N (%)
|
OR
|
OR (95 % CI)
|
|---|
|
Any medical condition
|
74 (47.7)
|
115 (61.5)
|
1.6
|
1.5 (0.9, 2.6)
|
57 (60.0)
|
1.6
|
1.2 (0.7, 2.3)
|
|
Infectious diseases
| | | | | | | |
|
Any infectious disease
|
32 (20.7)
|
44 (23.6)
|
1.1
|
1.0 (0.5, 1.7)
|
19 (20.0)
|
0.8
|
0.8 (0.4, 1.6)
|
|
Respiratory infection
|
18 (11.6)
|
21 (11.2)
|
1.0
|
0.9 (0.4, 2.0)
|
7 (7.4)
|
0.5
|
0.4 (0.1, 1.2)
|
|
Flu or cold
|
10 (6.5)
|
17 (9.1)
|
1.4
|
1.2 (0.5, 3.1)
|
3 (3.4)
|
0.4
|
0.3 (0.1, 1.4)
|
|
Other viral infections
|
1 (0.7)
|
5 (2.7)
|
3.8
|
3.6 (0.3, 47.9)
|
2 (2.1)
|
2.2
|
3.7 (0.3, 3.5)
|
|
Sexually transmitted infections
|
0 (0.0)
|
1 (0.5)
|
-
|
-
|
1 (1.1)
|
-
|
-
|
|
All bacterial infections
|
18 (11.6)
|
24 (12.8)
|
1.1
|
1.1 (0.5, 2.4)
|
11 (11.6)
|
0.9
|
0.8 (0.3, 2.1)
|
|
Urinary tract infections
|
6 (3.9)
|
9 (4.8)
|
1.1
|
0.8 (0.2, 3.0)
|
1 (1.1)
|
0.1
|
0.2 (0.1, 1.8)
|
|
Mother took antibiotics in pregnancy
|
21 (13.6)
|
22 (11.8)
|
0.8
|
0.8 (0.3, 1.8)
|
10 (10.5)
|
0.6
|
0.5 (0.2, 1.4)
|
|
Chronic diseases
| | | | | | | |
|
High blood pressure
|
17 (11.0)
|
23 (12.3)
|
1.1
|
1.2 (0.5, 2.6)
|
11 (11.6)
|
1.2
|
1.0 (0.4, 2.6)
|
|
Gestational high blood pressure
|
17 (11.0)
|
22 (11.8)
|
1.1
|
1.1 (0.5, 2.5)
|
11 (11.6)
|
1.2
|
1.0 (0.4, 2.6)
|
|
Diabetes (any)
|
6 (3.9)
|
17 (9.1)
|
2.5
|
2.2 (0.8, 6.6)
|
8 (8.4)
|
1.8
|
1.9 (0.6, 6.6)
|
|
Gestational diabetes
|
6 (3.9)
|
14 (7.5)
|
2.0
|
1.9 (0.6. 5.7)
|
8 (8.4)
|
1.8
|
1.9 (0.6, 6.6)
|
|
Preeclampsia
|
7 (4.5)
|
9 (4.8)
|
1.1
|
1.1 (0.3, 4.4)
|
2 (2.1)
|
0.7
|
0.6 (0.1, 4.0)
|
|
Endocrine disorders
| | | | | | | |
|
Any thyroid problem
|
2 (1.3)
|
6 (3.2)
|
2.2
|
2.2 (0.4, 12.3)
|
2 (2.1)
|
1.0
|
0.8 (0.1, 7.5)
|
|
Hypothyroidism
|
2 (1.3)
|
5 (2.7)
|
1.6
|
1.6 (0.3, 9.6)
|
2 (2.1)
|
1.0
|
0.8 (0.1, 7.4)
|
|
Pain and pain medication
| | | | | | | |
|
Back pain
|
4 (2.6)
|
11 (5.9)
|
2.5
|
3.4 (0.8, 14.4)
|
4 (4.2)
|
2.2
|
2.0 (0.3, 13.9)
|
|
Pain medication
|
3 (1.9)
|
8 (4.3)
|
2.3
|
4.2 (0.8, 23.3)
|
7 (7.4)
|
6.0
|
9.0 (1.4, 56.4)
|
|
Other Diseases and conditions
| | | | | | | |
|
Depression/anxiety
|
5 (3.2)
|
10 (5.4)
|
2.2
|
3.3 (0.7, 14.8)
|
5 (5.3)
|
2.3
|
3.8 (0.7, 21.8)
|
|
Anemia
|
1 (0.7)
|
6 (3.2)
|
4.5
|
2.8 (0.3, 27.0)
|
2 (2.1)
|
2.2
|
1.1 (0.1, 16.1)
|
|
Allergy/asthma
|
8 (5.2)
|
13 (7.0)
|
1.3
|
1.3 (0.5, 3.7)
|
7 (7.4)
|
1.3
|
1.7 (0.5, 5.9)
|
- aAdjusted for the matching variable, child’s age at interview
- bAdjusted for child age at interview, mother’s race/ethnicity, mother’s educational attainment, household income, mother’s age at birth, and maternal smoking in the month before or during pregnancy
