TY - BOOK PY - 2013 DA - 2013// TI - National Cancer Center, Japan. Vital Statistics Japan (Ministry of Health, Labour and Welfare) ID - ref1 ER - TY - JOUR AU - Egawa, S. AU - Toma, H. AU - Ohigashi, H. AU - Okusaka, T. AU - Nakao, A. AU - Hatori, T. PY - 2012 DA - 2012// TI - Japan pancreatic cancer registry; 30th year anniversary: Japan pancreas society JO - Pancreas VL - 41 UR - https://doi.org/10.1097/MPA.0b013e318258055c DO - 10.1097/MPA.0b013e318258055c ID - Egawa2012 ER - TY - JOUR AU - Natali, P. G. AU - Nicotra, M. R. AU - Bigotti, A. AU - Venturo, I. AU - Slamon, D. J. AU - Fendly, B. M. PY - 1990 DA - 1990// TI - Expression of the p185 encoded by HER2 oncogene in normal and transformed human tissues JO - Int J Cancer VL - 45 UR - https://doi.org/10.1002/ijc.2910450314 DO - 10.1002/ijc.2910450314 ID - Natali1990 ER - TY - JOUR AU - Slamon, D. J. AU - Clark, G. M. AU - Wong, S. G. AU - Levin, W. J. AU - Ullrich, A. AU - McGuire, W. L. PY - 1987 DA - 1987// TI - Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene JO - Science VL - 235 UR - https://doi.org/10.1126/science.3798106 DO - 10.1126/science.3798106 ID - Slamon1987 ER - TY - JOUR AU - Moasser, M. M. PY - 2007 DA - 2007// TI - The oncogene HER2: its signaling and transforming functions and its role in human cancer pathogenesis JO - Oncogene VL - 26 UR - https://doi.org/10.1038/sj.onc.1210477 DO - 10.1038/sj.onc.1210477 ID - Moasser2007 ER - TY - JOUR AU - Lewis, G. D. AU - Figari, I. AU - Fendly, B. AU - Wong, W. L. AU - Carter, P. AU - Gorman, C. PY - 1993 DA - 1993// TI - Differential responses of human tumor cell lines to anti-p185HER2 monoclonal antibodies JO - Cancer Immunol Immunother VL - 37 UR - https://doi.org/10.1007/BF01518520 DO - 10.1007/BF01518520 ID - Lewis1993 ER - TY - JOUR AU - Slamon, D. J. AU - Leyland-Jones, B. AU - Shak, S. AU - Fuchs, H. AU - Paton, V. AU - Bajamonde, A. PY - 2001 DA - 2001// TI - Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2 JO - N Engl J Med VL - 344 UR - https://doi.org/10.1056/NEJM200103153441101 DO - 10.1056/NEJM200103153441101 ID - Slamon2001 ER - TY - JOUR AU - Bang, Y. J. AU - Cutsem, E. AU - Feyereislova, A. AU - Chung, H. C. AU - Shen, L. AU - Sawaki, A. PY - 2010 DA - 2010// TI - Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial JO - Lancet VL - 376 UR - https://doi.org/10.1016/S0140-6736(10)61121-X DO - 10.1016/S0140-6736(10)61121-X ID - Bang2010 ER - TY - JOUR AU - Safran, H. AU - Steinhoff, M. AU - Mangray, S. AU - Rathore, R. AU - King, T. C. AU - Chai, L. PY - 2001 DA - 2001// TI - Overexpression of the HER-2/neu oncogene in pancreatic adenocarcinoma JO - Am J Clin Oncol VL - 24 UR - https://doi.org/10.1097/00000421-200110000-00016 DO - 10.1097/00000421-200110000-00016 ID - Safran2001 ER - TY - JOUR AU - Dergham, S. T. AU - Dugan, M. C. AU - Arlauskas, P. AU - Du, W. AU - Vaitkevicius, V. K. AU - Crissman, J. D. PY - 1997 DA - 1997// TI - Relationship of family cancer history to the expression of p53, p21WAF-1, HER-2/neu, and K-ras mutation in pancreatic adenocarcinoma JO - Int J Pancreatol VL - 21 UR - https://doi.org/10.1007/BF02821608 DO - 10.1007/BF02821608 ID - Dergham1997 ER - TY - JOUR AU - Yamanaka, Y. AU - Friess, H. AU - Kobrin, M. S. AU - Büchler, M. AU - Kunz, J. AU - Beger, H. G. PY - 1993 DA - 1993// TI - Overexpression of HER2/neu oncogene in human pancreatic carcinoma JO - Hum Pathol VL - 24 UR - https://doi.org/10.1016/0046-8177(93)90194-L DO - 10.1016/0046-8177(93)90194-L ID - Yamanaka1993 ER - TY - JOUR AU - Stoecklein, N. H. AU - Luebke, A. M. AU - Erbersdobler, A. AU - Knoefel, W. T. AU - Schraut, W. AU - Verde, P. E. PY - 2004 DA - 2004// TI - Copy number of chromosome 17 but not HER2 amplification predicts clinical outcome of patients with pancreatic ductal adenocarcinoma JO - J Clin Oncol VL - 22 UR - https://doi.org/10.1200/JCO.2004.05.142 DO - 10.1200/JCO.2004.05.142 ID - Stoecklein2004 ER - TY - JOUR AU - Novotný, J. AU - Petruzelka, L. AU - Vedralová, J. AU - Kleibl, Z. AU - Matous, B. AU - Juda, L. PY - 2001 DA - 2001// TI - Prognostic significance of c-erbB-2 gene expression in pancreatic cancer patients JO - Neoplasma VL - 48 ID - Novotný2001 ER - TY - JOUR AU - Safran, H. AU - Iannitti, D. AU - Ramanathan, R. AU - Schwartz, J. D. AU - Steinhoff, M. AU - Nauman, C. PY - 2004 DA - 2004// TI - Herceptin and gemcitabine for metastatic pancreatic cancers that overexpress HER-2/neu JO - Cancer Invest VL - 22 UR - https://doi.org/10.1081/CNV-200032974 DO - 10.1081/CNV-200032974 ID - Safran2004 ER - TY - JOUR AU - Harder, J. AU - Ihorst, G. AU - Heinemann, V. AU - Hofheinz, R. AU - Moehler, M. AU - Buechler, P. PY - 2012 DA - 2012// TI - Multicentre phase II trial of trastuzumab and capecitabine in patients with HER2 overexpressing metastatic pancreatic cancer JO - Br J Cancer VL - 106 UR - https://doi.org/10.1038/bjc.2012.18 DO - 10.1038/bjc.2012.18 ID - Harder2012 ER - TY - JOUR AU - Burris, H. A. AU - Tibbitts, J. AU - Holden, S. N. AU - Sliwkowski, M. X. AU - Lewis Phillips, G. D. PY - 2011 DA - 2011// TI - Trastuzumab emtansine (T-DM1): a novel agent for targeting HER2+ breast cancer JO - Clin Breast Cancer VL - 11 UR - https://doi.org/10.1016/j.clbc.2011.03.018 DO - 10.1016/j.clbc.2011.03.018 ID - Burris2011 ER - TY - JOUR AU - LoRusso, P. M. AU - Weiss, D. AU - Guardino, E. AU - Girish, S. AU - Sliwkowski, M. X. PY - 2011 DA - 2011// TI - Trastuzumab emtansine: a unique antibody-drug conjugate in development for human epidermal growth factor receptor 2-positive cancer JO - Clin Cancer Res VL - 17 UR - https://doi.org/10.1158/1078-0432.CCR-11-0762 DO - 10.1158/1078-0432.CCR-11-0762 ID - LoRusso2011 ER - TY - JOUR AU - Barok, M. AU - Tanner, M. AU - Köninki, K. AU - Isola, J. PY - 2011 DA - 2011// TI - Trastuzumab-DM1 causes tumour growth inhibition by mitotic catastrophe in trastuzumab-resistant breast cancer cells in vivo JO - Breast Cancer Res VL - 13 UR - https://doi.org/10.1186/bcr2868 DO - 10.1186/bcr2868 ID - Barok2011 ER - TY - JOUR AU - Barok, M. AU - Tanner, M. AU - Köninki, K. AU - Isola, J. PY - 2011 DA - 2011// TI - Trastuzumab-DM1 is highly effective in preclinical models of HER2-positive gastric cancer JO - Cancer Lett VL - 306 UR - https://doi.org/10.1016/j.canlet.2011.03.002 DO - 10.1016/j.canlet.2011.03.002 ID - Barok2011 ER - TY - JOUR AU - Verma, S. AU - Miles, D. AU - Gianni, L. AU - Krop, I. E. AU - Welslau, M. AU - Baselga, J. PY - 2012 DA - 2012// TI - Trastuzumab emtansine for HER2-positive advanced breast cancer JO - N Engl J Med VL - 367 UR - https://doi.org/10.1056/NEJMoa1209124 DO - 10.1056/NEJMoa1209124 ID - Verma2012 ER - TY - JOUR AU - Sipos, B. AU - Möser, S. AU - Kalthoff, H. AU - Török, V. AU - Löhr, M. AU - Klöppel, G. PY - 2003 DA - 2003// TI - A comprehensive characterization of pancreatic ductal carcinoma cell lines: towards the establishment of an in vitro research platform JO - Virchows Arch VL - 442 ID - Sipos2003 ER - TY - JOUR AU - Coombs, L. M. AU - Pigott, D. A. AU - Sweeney, E. AU - Proctor, A. J. AU - Eydmann, M. E. AU - Parkinson, C. PY - 1991 DA - 1991// TI - Amplification and over-expression of c-erbB-2 in transitional cell carcinoma of the urinary bladder JO - Br J Cancer VL - 63 UR - https://doi.org/10.1038/bjc.1991.139 DO - 10.1038/bjc.1991.139 ID - Coombs1991 ER - TY - JOUR AU - Potter, C. R. AU - Daele, S. AU - Vijiver, M. J. AU - Pauwels, C. AU - Maertens, G. AU - Boever, J. PY - 1989 DA - 1989// TI - The expression of the neu oncogene product in breast lesions and in normal fetal and adult human tissues JO - Histopathology VL - 15 UR - https://doi.org/10.1111/j.1365-2559.1989.tb01587.x DO - 10.1111/j.1365-2559.1989.tb01587.x ID - Potter1989 ER - TY - JOUR AU - Osako, T. AU - Miyahara, M. AU - Uchino, S. AU - Inomata, M. AU - Kitano, S. AU - Kobayashi, M. PY - 1998 DA - 1998// TI - Immunohistochemical study of c-erbB-2 protein in colorectal cancer and the correlation with patient survival JO - Oncology VL - 55 UR - https://doi.org/10.1159/000011911 DO - 10.1159/000011911 ID - Osako1998 ER - TY - JOUR AU - Burris, H. A. AU - Moore, M. J. AU - Andersen, J. AU - Green, M. R. AU - Rothenberg, M. L. AU - Modiano, M. R. PY - 1997 DA - 1997// TI - Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial JO - J Clin Oncol VL - 15 ID - Burris1997 ER - TY - JOUR AU - Wang, S. E. AU - Lin, R. J. PY - 2013 DA - 2013// TI - MicroRNA and HER2-overexpressing cancer JO - Microrna VL - 2 UR - https://doi.org/10.2174/22115366113029990011 DO - 10.2174/22115366113029990011 ID - Wang2013 ER - TY - JOUR AU - Scott, G. K. AU - Goga, A. AU - Bhaumik, D. AU - Berger, C. E. AU - Sullivan, C. S. AU - Benz, C. C. PY - 2007 DA - 2007// TI - Coordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125b JO - J Biol Chem VL - 282 UR - https://doi.org/10.1074/jbc.M609383200 DO - 10.1074/jbc.M609383200 ID - Scott2007 ER - TY - JOUR AU - Marx, C. AU - Yau, C. AU - Banwait, S. AU - Zhou, Y. AU - Scott, G. K. AU - Hann, B. PY - 2007 DA - 2007// TI - Proteasome-regulated ERBB2 and estrogen receptor pathways in breast cancer JO - Mol Pharmacol VL - 71 UR - https://doi.org/10.1124/mol.107.034090 DO - 10.1124/mol.107.034090 ID - Marx2007 ER - TY - JOUR AU - Marx, C. AU - Held, J. M. AU - Gibson, B. W. AU - Benz, C. C. PY - 2010 DA - 2010// TI - ErbB2 trafficking and degradation associated with K48 and K63 polyubiquitination JO - Cancer Res VL - 70 UR - https://doi.org/10.1158/0008-5472.CAN-09-3768 DO - 10.1158/0008-5472.CAN-09-3768 ID - Marx2010 ER - TY - JOUR AU - Nakachi, K. AU - Furuse, J. AU - Ishii, H. AU - Suzuki, E. AU - Yoshino, M. PY - 2007 DA - 2007// TI - Prognostic factors in patients with gemcitabine-refractory pancreatic cancer JO - Jpn J Clin Oncol VL - 37 UR - https://doi.org/10.1093/jjco/hyl144 DO - 10.1093/jjco/hyl144 ID - Nakachi2007 ER - TY - JOUR AU - Parsons, S. L. AU - Watson, S. A. AU - Steele, R. J. PY - 1996 DA - 1996// TI - Malignant ascites JO - Br J Surg VL - 83 UR - https://doi.org/10.1002/bjs.1800830104 DO - 10.1002/bjs.1800830104 ID - Parsons1996 ER - TY - JOUR AU - Kuwahara, K. AU - Sasaki, T. AU - Kobayashi, K. AU - Noma, B. AU - Serikawa, M. AU - Iiboshi, T. PY - 2004 DA - 2004// TI - Gemcitabine suppresses malignant ascites of human pancreatic cancer: correlation with VEGF expression in ascites JO - Oncol Rep VL - 11 ID - Kuwahara2004 ER -