Propensity-matched analysis of three different chemotherapy sequences in patients with locoregionally advanced nasopharyngeal carcinoma treated using intensity-modulated radiotherapy

Table 3 Comparison of the survival rates for each treatment group

Comparison	IC plus RT vs. CCRT	IC plus CCRT vs. CCRT	IC plus CCRT vs. IC plus RT
	(n = 98)	(n = 98)	(n = 98)
Three-year DFS	86.3 % vs. 82.1 %	87.8 % vs. 82.1 %	87.8 % vs. 86.3 %
P value^*	0.592	0.533	0.924
Three-year OS	91 % vs. 92.8 %	95.8 % vs. 92.8 %	95.8 % vs. 91 %
P value^*	0.987	0.318	0.390
Three-year DMFS	91.6 % vs. 87 %	93.8 % vs. 87 %	93.8 % vs. 91.6 %
P value^*	0.526	0.290	0.676
Three-year LRRFS	94.4 % vs. 90.4 %	93.9 % vs. 90.4 %	93.9 % vs. 94.4 %
P value^*	0.425	0.646	0.709

Abbreviations: IC induction chemotherapy, RT radiotherapy, CCRT concurrent chemoradiotherapy, DFS disease–free survival, OS overall survival, DMFS distant metastasis–free survival, LRRFS, Locoregional relapse–free survival
^*P-values were calculated using the unadjusted log–rank test

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