Table 1 Clinical characteristics of discovery case 1 and 2
Discovery case | Sex | Age at splenectomy | B-Symptoms | Leukemic disease (villous Lymphozytes) | Immunophenotype | Clinical staging at splenectomy | Oncological responsea |
|---|---|---|---|---|---|---|---|
1 | f | 59 | yes | no | CD20+++, IgM-, Kappa-, Lambda-, Ki-67 5 %, CD5-, CD3-, Cyclin-D1-, bcl-2++ | IV | CR |
2 | f | 59 | yes | no | CD20+++, IgM+, Kappa-, Lambda-, Ki-67 15 %, CD5-, CD3-, Cyclin-D1-, bcl-2++ | IV | CR |