Fig. 3

Sanger sequencing of SMYD1. All exons of the SMYD1 gene were sequenced using conventional Sanger sequencing. Only forward sequences are shown, reverse sequencing showed corresponding results. Schematic illustration of the gene and the mutations identified. Exons with mutations are depicted in green and those without mutations in blue. SIFT and PolyPhen-2 predictions for SMYD1 mutations are shown in the table