Table 4 Multivariate Cox-regression models applied to the adherence index and crucial risk, prognosis and predictive factors

 Adherence index

−0.373

0.436

0.392

0.688

0.293

1.619

 Age at surgery

−0.044

0.069

0.525

0.957

0.836

1.069

 Nodal status (pN-, pN+)

1.049

0.263

<0.001

2.854

1.706

4.775

 Tumor size (pT2, pT2-pT4)

0.121

0.244

0.620

1.129

0.700

1.821

 Hormon receptor status (ERPR+, ERPR-)

0.602

0.313

0.055

1.825

0.988

3.371

 Quadratic term of age at surgery

0.001

0.001

0.132

1.001

1.000

1.002

 Adherence index

−0.162

0.489

0.740

0.850

0.326

2.217

 Age at surgery

−0.058

0.083

0.483

0.943

0.801

1.111

 Nodal status (pN-, pN+)

1.184

0.336

<0.001

3.269

1.692

6.316

 Tumor size (pT2, pT2-pT4)

0.015

0.307

0.961

1.015

0.556

1.854

 Hormon receptor status (ERPR+, ERPR-)

0.664

0.389

0.088

1.942

0.907

4.162

 Quadratic term of age at surgery

0.001

0.001

0.188

1.001

1.000

1.002

 Adherence index

−0.135

0.350

0.699

0.873

0.440

1.733

 Age at surgery

−0.089

0.080

0.266

0.915

0.782

1.070

 Nodal status (pN-, pN+)

0.931

0.307

0.002

2.537

1.391

4.627

 Tumor size (pT2, pT2-pT4)

0.615

0.302

0.042

1.850

1.023

3.344

 Hormon receptor status (ERPR+, ERPR-)

1.196

0.310

<0.001

3.307

1.801

6.075

 Quadratic term of age at surgery

0.001

0.001

0.173

1.001

1.000

1.002

 Adherence index

−0.638

0.467

0.172

0.529

0.212

1.320

 Age at surgery

−0.151

0.090

0.093

0.859

0.720

1.025

 Nodal status (pN-, pN+)

0.500

0.375

0.182

1.648

0.791

3.437

 Tumor size (pT2, pT2-pT4)

0.512

0.371

0.168

1.668

0.806

3.450

 Hormon receptor status (ERPR+, ERPR-)

1.048

0.367

0.004

2.853

1.389

5.861

 Quadratic term of age at surgery

0.001

0.001

0.070

1.001

1.000

1.003