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Table 4 Cox multivariate analysis of GATA4 expression/promoter methylation and clinico-pathological features in pediatric AML

From: Hypermethylation of the GATA binding protein 4 (GATA4) promoter in Chinese pediatric acute myeloid leukemia

Variable Odds ratio EXP(B) 95 % CI P
Cytogenetics
 Favo vs. Inter and Unfavo 5.894 2.412 (1.185–4.909) 0.015
MRD
  < 0.25 % vs. ≥0.25 % 16.241 5.986 (2.503–14.229) 0.000
Leukocyte (/μl)
  > 10,000 vs. ≤10,000 0.485 1.225 (0.691–2.172) 0.486
FAB classification
 M7 vs. M1–M6 6.645 2.630 (1.261–5.484) 0.010
GATA4 Expression
 Low vs. High 2.765 1.657 (0.914–3.007) 0.096
GATA4 Methylation
 Negative vs. Positive 1.885 0.661 (0.367–1.193) 0.170