Skip to main content

Table 3 Association of GATA4 expression/promoter methylation with Kaplan-Meier survival in 105 pediatric AML samples

From: Hypermethylation of the GATA binding protein 4 (GATA4) promoter in Chinese pediatric acute myeloid leukemia

Variable No. of patients Over survival P
Median ± SE
Cytogenetics
 Favorable 50 46.664 ± 3.717 <0.001
 Intermediate 27 29.220 ± 3.188  
 Unfavorable 28 11.161 ± 1.827  
FAB
 M1–M6 93 36.113 ± 2.885 <0.001
 M7 12 8.542 ± 1.820  
Leukocyte (/μl)
  > 10,000 61 30.220 ± 2.974 0.803
  ≤ 10,000 44 33.631 ± 4.063  
MRD
  < 0.25 % 49 53.627 ± 3.151 <0.001
  ≥ 0.25 % 56 18.893 ± 2.425  
GATA4 expression
 Low <12.420 53 32.130 ± 3.385 0.769
 High ≥12.420 52 34.765 ± 3.941  
GATA4 methylation
 Negative 46 39.141 ± 3.554 0.014
 Positive 59 24.264 ± 3.671