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Fig. 1 | BMC Cancer

Fig. 1

From: Isolation of vaccinia JX594 from pustules following therapy for hepatocellular carcinoma

Fig. 1

a The patient developed a pustular lesion on the proximal interphalangeal joint of the right middle fingerfollowing intravenous injection with JX594. b Other pustular lesions were noted on the both sides of the tongue dorsum. c The cytopathic effect was observed by co-culturing the virus with MRC-5 cells. Asterisk: normal MRC-5 cells structure; Thin arrow: discohesive structure; Bold arrow: rounded cell; Arrowhead: necrotic debris and vesicles. d PCR designed to amplify the JX-594-specific hGM-CSF transgene (Primer pair 1) and the disrupted viral thymidine kinase gene (Primer pair 2) was positive. M, marker; NC, negative control

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