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Table 3 Disease free survival and ROS1 expression

From: Clinical and pathological significance of ROS1 expression in intrahepatic cholangiocarcinoma

  

Univariate

Multivariate

  

Median(m)

p.

HR [95 % CI]

p.

ROS1 expression

Negative vs. positive

9 vs. 30

0.006

0.58 [0.37–0.89]

0.014

Size of tumor

Cm

1.053a

0.008

1.06 [1.01–1.11]

0.019

Number of tumor

Single vs. multiple

15 vs. 4

0.001

2.27 [1.24–4.16]

0.008

Gross type

Mass forming vs. periductal

9 vs. 89

<0.001

0.48 [0.24–0.98]

0.042

Differentiation

Well vs. moderate to poor

89 vs. 9

<0.001

2.22 [1.09–4.51]

0.028

Perineural invasion

Absent vs. present

19 vs. 9

0.039

1.63 [1.04–2.55]

0.034

Vascular invasion

Absent vs present

15 vs. 8

0.051

  

Lymphatic invasion

Absent vs present

19 vs. 8

0.009

  

Histologic type

Papillary/mucinous vs.

NA vs. 11

0.026

  
 

Tubular/undifferentiated

    
  1. aMean hazard ratio by Cox proportional hazard model; HR, hazard ratio; CI, confidential interval
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BMC Cancer

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