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Table 1 Associations between SUSD4 and clinical parameters

From: The human complement inhibitor Sushi Domain-Containing Protein 4 (SUSD4) expression in tumor cells and infiltrating T cells is associated with better prognosis of breast cancer patients

Factor

 

Patient

SUSD4+ tumor cells

 

Patient

SUSD4+ infiltrating cells

 
   

No

Yes

P *

 

0-15

16-100

P *

 

N

   

N

   

All

123

46 (37)

77 (63)

 

123

87 (71)

36 (29)

 

Age at diagnosis

123

  

0.047

123

  

0.006

 Median (min, max)

 

63 (34, 97)

67 (35, 91)

  

68 (34, 97)

61 (41, 79)

 

Tumor size,

123

  

0.066

123

   

 Median mm (min, max)

 

23.5 (10, 73)

21 (7, 145)

  

23 (8, 145)

19.5 (8, 73)

0.143

NHG

   

<0.001

   

0.045

 I

N (%)

15

2 (13)

13 (87)

 

17

11 (65)

6 (35)

 

 II

58

16 (28)

42 (72)

 

56

35 (63)

21 (37)

 

 III

50

28 (56)

22 (44)

 

50

41 (82)

9 (18)

 

Nodal status

   

0.027

   

0.853

 0

N (%)

58

16 (28)

42 (72)

 

60

42 (70)

18 (30)

 

 1-3

34

14 (41)

20 (59)

 

32

23 (72)

9 (28)

 

 >4

18

10 (56)

8 (44)

 

18

13 (72)

5 (28)

 

 Missing

13

   

13

   

ER status

   

0.008

   

0.041

 Negative

N (%)

18

12 (67)

6 (33)

 

17

16 (94)

1 (6)

 

 Positive

105

34 (32)

71 (68)

 

106

71 (67)

35 (33)

 

PR status

   

0.117

   

0.295

 Negative N (%)

 

40

19 (48)

21 (52)

 

40

31 (78)

9 (22)

 

 Positive

83

27 (32)

56 (68)

 

83

56 (68)

27 (32)

 

HER2

   

0.013

   

1.000

 Negative

N (%)

112

38 (34)

74 (66)

 

106

77 (73)

29 (27)

 

 Positive

9

7 (78)

2 (22)

 

11

8 (73)

3 (27)

 

 Missing

2

   

6

   

Ki67

   

0.239

   

0.136

 0-24 %

N (%)

50

17 (34)

33 (66)

 

52

34 (65)

18 (35)

 

 >25 %

58

27 (47)

31 (53)

 

57

45 (79)

12 (21)

 

 Missing

15

   

14

   
  1. *Mann–Whitney, 2-tailed Exact p-value