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Fig. 1 | BMC Cancer

Fig. 1

From: Correlation between apparent diffusion coefficients and HER2 status in gastric cancers: pilot study

Fig. 1

A 69-year-old man with gastric cancer, at stage IIIA (T3N2M0). Axial diffusion weighted image (b = 1000 sec/mm2) (a) shows the lesion with remarkably high signal intensity in antrum (arrow) of stomach with a maximum diameter of 5.0 cm. An oval region-of-interest (ROI) with an area of 43.7 mm2 is placed within the solid part of the lesion in corresponding apparent diffusion coefficient (ADC) map (b), which shows restricted mean and minimal ADC values as 1.148 and 0.970 × 10−3 mm2/s respectively. Photomicrograph (Hematoxylin & Eosin staining, ×200) (c) proves moderately differentiated adenocarcinoma with a Lauren classification of intestinal type. HER2 immunohistochemical assay (d) shows complete and intense circumferential membrane staining in >10 % of tumor cells (score 3+)

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