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Table 1 Clinical details of patients treated with surgical resection of gastroesophageal cancers

From: Regulation of cellular sphingosine-1-phosphate by sphingosine kinase 1 and sphingosine-1-phopshate lyase determines chemotherapy resistance in gastroesophageal cancer

Variable

Score

Neo-adjuvant Chemotherapy

No Neo-adjuvant Chemotherapy

P value*

Age

>Median

9

15

0.073

< Median

27

16

Histology

Adenocarcinoma

31

24

0.180

Squamous

5

7

Stage

I

11

3

0.109

II

10

12

III

15

16

Site

Oesophagus

30

25

0.755

(includes Siewert Type I and II junctional)

  
 

6

6

Gastric

  

(includes Siewert Type III junctional)

  

Circumferential Resection Margins

Positive

6

11

0.378

Negative

30

20

  1. There was no significant difference in clinic-pathological characteristics between patients who did and did not receive neo-adjuvant chemotherapy prior to surgery. SPHK1 immunohistochemistry was performed on this cohort as described. *χ2 test. Two-sided p value