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Table 1 Clinical details of patients treated with surgical resection of gastroesophageal cancers

From: Regulation of cellular sphingosine-1-phosphate by sphingosine kinase 1 and sphingosine-1-phopshate lyase determines chemotherapy resistance in gastroesophageal cancer

Variable Score Neo-adjuvant Chemotherapy No Neo-adjuvant Chemotherapy P value*
Age >Median 9 15 0.073
< Median 27 16
Histology Adenocarcinoma 31 24 0.180
Squamous 5 7
Stage I 11 3 0.109
II 10 12
III 15 16
Site Oesophagus 30 25 0.755
(includes Siewert Type I and II junctional)   
  6 6
Gastric   
(includes Siewert Type III junctional)   
Circumferential Resection Margins Positive 6 11 0.378
Negative 30 20
  1. There was no significant difference in clinic-pathological characteristics between patients who did and did not receive neo-adjuvant chemotherapy prior to surgery. SPHK1 immunohistochemistry was performed on this cohort as described. *χ2 test. Two-sided p value