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Table 4 Clinical adverse effects

From: Transarterial injection of recombinant human type-5 adenovirus H101 in combination with transarterial chemoembolization (TACE) improves overall and progressive-free survival in unresectable hepatocellular carcinoma (HCC)

 

Overall

H101

Control

P value

Fever

   

0.023

  > 38.5 °C

55.4 %

64.4 %

46.6 %

 

  ≤ 38.5 °C

44.6 %

35.6 %

53.4 %

 

Pain

   

0.875

 Yes

65.1 %

64.4 %

65.9 %

 

 No

34.9 %

35.6 %

34.1 %

 

Ascites

   

0.864

 Yes

25.7 %

26.4 %

25 %

 

 No

74.3 %

73.6 %

75 %

 

Acute renal failure

    

 Yes

5.1 %

5.7 %

4.5 %

0.896

 No

94.9 %

94.3 %

95.5 %

 

Encephalopathy

    

 Yes

0

0

0

 

 No

100 %

100 %

100 %

 

White Blood Cell

    

 Before TACE

5.7

6.0

5.5

0.369

 After TACE

7.64

7.0

8.84

0.991

 Elevation

1.61

0.5

2.97

0.001

PLT

    

 Before

167.0

179.2

154.5

0.186

 After

113.0

122.8

106.1

0.258

 Elevation

49.0

52.7

48.4

0.480

ALT

    

 Before

41.5

43.2

41.4

0.371

 After

167.1

153.0

200.9

0.405

 Elevation

103.1

88.1

118.4

0.480

AST

    

 Before

50.9

57.1

46.4

0.249

 After

221.3

225.4

213.5

0.993

 Elevation

154.2

141.2

162.0

0.863

TBIL

    

 Before

16.3

16.1

16.8

0.657

 After

30.4

28.3

31.8

0.162

 Elevation

12.9

12.4

13.25

0.413

ALB

    

 Before

40.0

38.2

41.2

0.161

 After

35.4

34.1

37.0

0.314

 Elevation

4.1

3.6

4.4

0.226

  1. PLT platelet count, ALB albumin, ALT alanine aminotransferase, AST aspartate aminotransferase, PLT platelet, TACE transhepatic arterial chemoembolization, TBIL total bilirubin