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Fig. 6 | BMC Cancer

Fig. 6

From: The regulatory and predictive functions of miR-17 and miR-92 families on cisplatin resistance of non-small cell lung cancer

Fig. 6

The expressions of miR-17 and miR-92 families were associated with the clinical outcome of platinum-based chemotherapy. a Scatter plots of expression levels of miR-17, miR-20a, miR-20b, miR-92a, miR-92b, miR-25 in responders and non-responders (NR, non-responder (stable or progressive disease); R, responder (response or partial response)). (*P < 0.05) b ROC analysis assessing the association the expressions of miR-17 and 92 families and the clinical outcome of platinum-based chemotherapy (NR or R) by miR-17, miR-20a, miR-20b, miR-92a, miR-92b, miR-25 levels as continuous variables, and combinations of miR-17, miR-20a, miR-20b, miR-92a, miR-92b, miR-25 levels using the sum of scores as categorical variables, where each miRNA was dichotomised and its categories represented by the score of 0 or 1 as follows: score 0 (low risk) = miR-17, miR-20a, miR-20b, miR-92a, miR-92b, miR-25 levels ≥ median; score 1(high risk) = converse of criteria for score 0

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