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Fig. 5 | BMC Cancer

Fig. 5

From: Downregulation of programmed cell death 10 is associated with tumor cell proliferation, hyperangiogenesis and peritumoral edema in human glioblastoma

Fig. 5

The association of PDCD10 expression and the grade of brain edema in GBM. a Grading peritumoral edema in GBM. The grade of peritumoral edema in GBM was evaluated based on magnetic resonance imaging (MRI). b The association of PDCD10 protein expression and the grade of edema. The expression of PDCD10 was inversely correlated to the grade of peritumoral edema. *** p < 0.001, compared to edema grade 0. c and d The expression of total RhoA and phosphor-MLC2 (p-MLC2) in GBM. The expression of RhoA and phosphor-MLC2 (p-MLC2) appeared to be increased in GBM compared to the control (c) but did not show statistically significant difference (c). Thus, downregulation of PDCD10 did not seem to be correlated to the activation of RhoA signaling. The representative blots are shown in d. ** p < 0.01, compared with control (c)

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