Skip to main content

Advertisement

Table 2 Taqman genotyping (rs725605-CA1) result (control n = 288)

From: CA1 contributes to microcalcification and tumourigenesis in breast cancer

SNP identity-gene Breast cancer n = 278 Rectal carcinoma n = 132 Colon carcinoma n = 140 Cervical carcinoma n = 179 Esophageal carcinoma n = 259 Gastric carcinoma n = 263 Liver cancer n = 186 Lung carcinoma n = 181
Allele A G A G A G A G A G A G A G A G
Case (freq) 220 (0.396) 118 (0.447) 113 (0.404) 163 (0.455) 252 (0.486) 232 (0.441) 162 (0.435) 174 (0.481)
336 (0.604) 146 (0.553) 167 (0.596) 195 (0.545) 266 (0.514) 294 (0.559) 210 (0.565) 188 (0.519)
Control (freq) 270 (0.475) 270 (0.475) 270 (0.475) 270 (0.475) 270 (0.475) 270 (0.475) 270 (0.475) 270 (0.475)
298 (0.525) 298 (0.525) 298 (0.525) 298 (0.525) 298 (0.525) 298 (0.525) 298 (0.525) 298 (0.525)
Odds Ratio (% 95 CI) 0.722663 0.892034 0.746817 0.922583 1.045614 0.870950 0.851429 1.021513
(0.570361~0.915634) (0.665320~1.196004) (0.558798~0.998101) (0.707594~1.202893) (0.823876~1.327031) (0.686340~1.105216) (0.654582~1.107471) (0.784591~1.329979)
Fisher’s p value 0.0071 0.44502 0.0483 0.55165 0.714 0.255551 0.230431 0.874386
Genotype A/A A/A A/A A/A A/A A/A A/A A/A
A/G A/G A/G A/G A/G A/G A/G A/G
G/G G/G G/G G/G G/G G/G G/G G/G
Case (freq) 49 (0.176) 23 (0.174) 21 (0.150) 38 (0.212) 51 (0.197) 53 (0.202) 33 (0.177) 41 (0.227)
122 (0.439) 72 (0.545) 71 (0.507) 87 (0.486) 150 (0.579) 126 (0.479) 96 (0.516) 92 (0.508)
107 (0.385) 37 (0.280) 48 (0.343) 54 (0.302) 58 (0.224) 84 (0.319) 57 (0.306) 48 (0.265)
Control (freq) 67 (0.236) 67 (0.236) 67 (0.236) 67 (0.236) 67 (0.236) 67 (0.236) 67 (0.236) 67 (0.236)
136 (0.479) 136 (0.479) 136 (0.479) 136 (0.479) 136 (0.479) 136 (0.479) 136 (0.479) 136 (0.479)
81 (0.285) 81 (0.285) 81 (0.285) 81 (0.285) 81 (0.285) 81 (0.285) 81 (0.285) 81 (0.285)
Fisher’s p value 0.029 0.30265 0.1048 0.825315 0.063 0.53125 0.317314 0.820064
HWE for case (df = 1) 0.1697 0.23526 0.527 0.787951 0.01 0.645998 0.497597 0.807632
HWE for control (df = 1) 0.5011 0.50114 0.5011 0.501122 0.501 0.501136 0.501122 0.501122