| Total | > 5 kg loss | 2.1–5 kg loss | ± 2 kg | 2–4.9 kg gain | ≥ 5 kg gain | p-value* |
---|---|---|---|---|---|---|---|
 |  | N (%) | N (%) | N (%) | N (%) | N (%) |  |
Total | 522 | 16 (3.1) | 80 (15.3) | 196 (37.5) | 136 (26.1) | 94 (18.0) | Â |
Baseline BMIa | |||||||
 Normal or underweight | 184 | 2 (1.1) | 16 (8.7) | 63 (34.2) | 46 (25.0) | 57 (31.0) | < 0.001 |
 Overweight | 152 | 3 (2.0) | 23 (15.1) | 58 (38.2) | 45 (29.6) | 23 (15.1) | < 0.001 |
 Obese | 186 | 11 (5.9) | 41 (22.0) | 75 (40.3) | 45 (24.2) | 14 (7.5) |  |
Age | |||||||
  < 65 years | 366 | 11 (3.0) | 52 (14.2) | 128 (35.0) | 97 (26.5) | 78 (21.3) | 0.006 |
  ≥ 65 years | 156 | 5 (3.2) | 28 (17.9) | 68 (43.6) | 39 (25.0) | 16 (10.3) | 0.003 |
Sex | |||||||
 Male | 312 | 11 (3.5) | 57 (18.3) | 115 (36.9) | 71 (22.8) | 58 (18.6) | 0.11 |
 Female | 210 | 5 (2.4) | 23 (11.0) | 81 (38.6) | 65 (31.0) | 36 (17.1) | 0.67 |
Location | |||||||
 Proximal | 181 | 3 (1.7) | 30 (16.6) | 66 (36.5) | 45 (24.9) | 37 (20.4) | 0.40 |
 Distal | 341 | 13 (3.8) | 50 (14.7) | 130 (38.1) | 91 (26.7) | 57 (16.7) | 0.29 |
T stage | |||||||
 T1 - 3 | 446 | 16 (3.6) | 67 (15.0) | 175 (39.2) | 112 (25.1) | 76 (17.0) | 0.056 |
 T4 | 76 | 0 (0.0) | 13 (17.1) | 21 (27.6) | 24 (31.6) | 18 (23.7) | 0.16 |
N stage | |||||||
 N0 - 1 | 380 | 10 (2.9) | 61 (16.1) | 142 (37.4) | 105 (27.6) | 62 (16.3) | 0.55 |
 N2 | 142 | 6 (4.2) | 19 (13.4) | 54 (38.0) | 31 (21.8) | 32 (22.5) | 0.10 |
Tumor stage | |||||||
 II, high-risk | 78 | 2 (2.6) | 9 (11.5) | 24 (30.8) | 29 (37.2) | 14 (17.9) | 0.15 |
 III | 444 | 14 (3.2) | 71 (16.0) | 172 (38.7) | 107 (24.1) | 80 (18.0) | 1.00 |
Histology | |||||||
 MAC | 27 | 1 (3.7) | 5 (18.5) | 6 (22.2) | 5 (18.5) | 10 (37.0) | 0.180 |
 Non-MAC | 495 | 15 (3.0) | 75 (15.2) | 190 (38.4) | 131 (26.5) | 84 (17.0) | 0.017** |
Microsatellite status (N = 517) | |||||||
 MSS + MSI-L | 480 | 14 (2.9) | 73 (15.2) | 186 (38.8) | 124 (25.8) | 83 (17.3) | 0.33 |
 MSI-H | 37 | 1 (2.7) | 7 (18.9) | 9 (24.3) | 10 (27.0) | 10 (27.0) | 0.14 |