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Table 2 Body weight change and baseline characteristics

From: Prognostic influence of body mass index and body weight gain during adjuvant FOLFOX chemotherapy in Korean colorectal cancer patients

  Total > 5 kg loss 2.1–5 kg loss ± 2 kg 2–4.9 kg gain ≥ 5 kg gain p-value*
   N (%) N (%) N (%) N (%) N (%)  
Total 522 16 (3.1) 80 (15.3) 196 (37.5) 136 (26.1) 94 (18.0)  
Baseline BMIa
 Normal or underweight 184 2 (1.1) 16 (8.7) 63 (34.2) 46 (25.0) 57 (31.0) < 0.001
 Overweight 152 3 (2.0) 23 (15.1) 58 (38.2) 45 (29.6) 23 (15.1) < 0.001
 Obese 186 11 (5.9) 41 (22.0) 75 (40.3) 45 (24.2) 14 (7.5)  
Age
  < 65 years 366 11 (3.0) 52 (14.2) 128 (35.0) 97 (26.5) 78 (21.3) 0.006
  ≥ 65 years 156 5 (3.2) 28 (17.9) 68 (43.6) 39 (25.0) 16 (10.3) 0.003
Sex
 Male 312 11 (3.5) 57 (18.3) 115 (36.9) 71 (22.8) 58 (18.6) 0.11
 Female 210 5 (2.4) 23 (11.0) 81 (38.6) 65 (31.0) 36 (17.1) 0.67
Location
 Proximal 181 3 (1.7) 30 (16.6) 66 (36.5) 45 (24.9) 37 (20.4) 0.40
 Distal 341 13 (3.8) 50 (14.7) 130 (38.1) 91 (26.7) 57 (16.7) 0.29
T stage
 T1 - 3 446 16 (3.6) 67 (15.0) 175 (39.2) 112 (25.1) 76 (17.0) 0.056
 T4 76 0 (0.0) 13 (17.1) 21 (27.6) 24 (31.6) 18 (23.7) 0.16
N stage
 N0 - 1 380 10 (2.9) 61 (16.1) 142 (37.4) 105 (27.6) 62 (16.3) 0.55
 N2 142 6 (4.2) 19 (13.4) 54 (38.0) 31 (21.8) 32 (22.5) 0.10
Tumor stage
 II, high-risk 78 2 (2.6) 9 (11.5) 24 (30.8) 29 (37.2) 14 (17.9) 0.15
 III 444 14 (3.2) 71 (16.0) 172 (38.7) 107 (24.1) 80 (18.0) 1.00
Histology
 MAC 27 1 (3.7) 5 (18.5) 6 (22.2) 5 (18.5) 10 (37.0) 0.180
 Non-MAC 495 15 (3.0) 75 (15.2) 190 (38.4) 131 (26.5) 84 (17.0) 0.017**
Microsatellite status (N = 517)
 MSS + MSI-L 480 14 (2.9) 73 (15.2) 186 (38.8) 124 (25.8) 83 (17.3) 0.33
 MSI-H 37 1 (2.7) 7 (18.9) 9 (24.3) 10 (27.0) 10 (27.0) 0.14
  1. Abbreviations: MAC mucinous adenocarcinoma, MSS microsatellite stable, MSI-L microsatellite instability-low, MSI-H microsatellite instability-high
  2. *Upper row: linear-by-linear association test, lower row: Χ2 test of ≥ 5 kg gain group vs. the others
  3. **Fisher’s exact test of ≥ 5 kg gain group vs. the others
  4. aNormal or underweight, ≤ 22.9 kg/m2; overweight, 23–24.9 kg/m2; and obese, BMI ≥ 25 kg/m2