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Table 4 Association between UGT1A1 genotypes and either prognostic factors or Grade 3 to 4 toxicities (n = 23)

From: Genomic profile predicts the efficacy of neoadjuvant chemotherapy for cervical cancer patients

UGT1A1 genotypes *1/*6 or*1/*28 *1/*1 p
n = 11 n = 12
Prognostic factors
 LVSI 5 (45 %) 6 (50 %) 0.827
 Shrinkage rate (median +/− SD %) 77.5 +/− 26.8 49.5 +/− 24.1 0.028*
G3/4 Toxicities
 Neutropenia 6 (54.5 %) 8 (66.7 %) 0.552
 Leukopenia 4 (36.4 %) 3 (25.0 %) 0.554
 Anemia 2 (18.2 %) 1 (8.3 %) 0.484
 Thrombocytopenia 1 (9.1 %) 0 0.286
 Diarrhea 2 (18.2 %) 1 (8.3 %) 0.484
 Vomiting 1 (9.1 %) 0 0.286
  1. *significant p-value