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Table 3 Clinical outcomes after trabectedin therapy

From: Efficacy of trabectedin in malignant solitary fibrous tumors: a retrospective analysis from the French Sarcoma Group

Pt no.

Best RECIST response

PFS (months)

Progression

OS (months)

Status at last follow-up

GMI = TTP2/TTP1

TTP1 (months)

TTP2 (months)

GMI

1

SD

11.7

N

11.7

Alive

4.9

-

-

2

SD

11.6

Y

29.2

Alive

5.6

11.6

2.07

3

SD

3.8

Y

9.1

Dead

1.9

3.8

2.02

4

SD

14.6

Y

22.3

Dead

12.6

14.6

1.16

5

SD

30.9

N

30.8

Alive

7.1

-

-

6

SD

11.0

Y

20.9

Alive

3.1

11.0

3.61

7

PD

1.9

Y

7.0

Dead

18.7

1.9

0.11

8

PR

7.5

Y

23.4

Dead

5.1

7.5

1.49

9

PD

2.0

Y

11.1

Dead

7.7

2.0

0.26

10

SD

15.2

Y

17.7

Dead

25.3

15.2

0.6

11

SD

12.3

Y

74.2

Alive

3.0

12.3

4.12

Median

 

11.6

 

22.3

 

5.6

11.6

1.49

  1. SD stable disease, PR partial response, PD progressive disease, GMI growth modulation index, TTP1 time to progression with the prior last-line treatment, TTP2 time to progression with trabectedin