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Table 4 Univariate analysis of DFS and OS according to PELP1 protein expression in different subgroups

From: Prognostic significance of proline, glutamic acid, leucine rich protein 1 (PELP1) in triple-negative breast cancer: a retrospective study on 129 cases

Variables Subgroup DFS OS
χ 2 P-value χ 2 P-value
Age (years)      
  ≤50 1.636 0.201 1.759 0.185
  >50 1.183 0.277 1.246 0.264
Tumor size (cm)a      
  ≤2 4.274 0.039 3.398 0.065
  >2, ≤5 0.441 0.507 0.813 0.367
  >5 1.936 0.164 1.134 0.284
Lymph node stage      
  negative 0.251 0.617 0.008 0.927
  positive 0.770 0.380 1.974 0.160
Grade      
  G1 1.864 0.172 0.688 0.407
  G2 2.369 0.124 2.327 0.127
  G3 0.188 0.665 0.461 0.497
Clinical stagea      
  I 1.231 0.267 1.250 0.264
  II 0.258 0.612 0.009 0.926
  III and IV 1.814 0.178 3.220 0.073
Histological type      
  IDC 1.278 0.258 1.399 0.237
  ILC 1.780 0.182 1.591 0.207
  Others 0.928 0.335 0.928 0.335
Ki-67 LI      
  Low (≤14 %) 0.148 0.700 0.161 0.688
  High (>14 %) 5.069 0.024 5.559 0.018
Chemotherapy      
  AC 1.144 0.285 1.192 0.275
  AC-T 1.910 0.157 1.871 0.171
  Others 0.000 0.994 0.500 0.480
Radiotherapy      
  No 2.806 0.094 3.262 0.071
  Yes 0.460 0.498 0.488 0.485
  1. Abbreviations: LN, lymph node; IDC, invasive ductal carcinoma; ILC, invasive lobular carcinoma; Ki-67 LI, Ki-67 label index; AC, Adriamycin/Cyclophosphamide; AC-T, Adriamycin/Cyclophosphamide-Taxol; DFS, disease-free survival; OS, overall survival
  2. Note: afor the variable, data for two cases are unavailable from medical records