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Table 4 Univariate analysis of DFS and OS according to PELP1 protein expression in different subgroups

From: Prognostic significance of proline, glutamic acid, leucine rich protein 1 (PELP1) in triple-negative breast cancer: a retrospective study on 129 cases

Variables

Subgroup

DFS

OS

χ 2

P-value

χ 2

P-value

Age (years)

     
 

≤50

1.636

0.201

1.759

0.185

 

>50

1.183

0.277

1.246

0.264

Tumor size (cm)a

     
 

≤2

4.274

0.039

3.398

0.065

 

>2, ≤5

0.441

0.507

0.813

0.367

 

>5

1.936

0.164

1.134

0.284

Lymph node stage

     
 

negative

0.251

0.617

0.008

0.927

 

positive

0.770

0.380

1.974

0.160

Grade

     
 

G1

1.864

0.172

0.688

0.407

 

G2

2.369

0.124

2.327

0.127

 

G3

0.188

0.665

0.461

0.497

Clinical stagea

     
 

I

1.231

0.267

1.250

0.264

 

II

0.258

0.612

0.009

0.926

 

III and IV

1.814

0.178

3.220

0.073

Histological type

     
 

IDC

1.278

0.258

1.399

0.237

 

ILC

1.780

0.182

1.591

0.207

 

Others

0.928

0.335

0.928

0.335

Ki-67 LI

     
 

Low (≤14 %)

0.148

0.700

0.161

0.688

 

High (>14 %)

5.069

0.024

5.559

0.018

Chemotherapy

     
 

AC

1.144

0.285

1.192

0.275

 

AC-T

1.910

0.157

1.871

0.171

 

Others

0.000

0.994

0.500

0.480

Radiotherapy

     
 

No

2.806

0.094

3.262

0.071

 

Yes

0.460

0.498

0.488

0.485

  1. Abbreviations: LN, lymph node; IDC, invasive ductal carcinoma; ILC, invasive lobular carcinoma; Ki-67 LI, Ki-67 label index; AC, Adriamycin/Cyclophosphamide; AC-T, Adriamycin/Cyclophosphamide-Taxol; DFS, disease-free survival; OS, overall survival
  2. Note: afor the variable, data for two cases are unavailable from medical records