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Table 2 Correlation between PELP1 protein expression and clinicopathological variables in patients with TNBC

From: Prognostic significance of proline, glutamic acid, leucine rich protein 1 (PELP1) in triple-negative breast cancer: a retrospective study on 129 cases

Variables

n

Status of PELP1 protein expression

P-value

low

high

Age (years)

    

 ≤50

69

31 (44.9 %)

38 (55.1 %)

0.843

 >50

60

28 (46.7 %)

32 (53.3 %)

 

Tumor size (cm)a

    

 ≤2

31

13 (41.9 %)

18 (58.1 %)

0.635

 >2, ≤5

74

33 (44.6 %)

41 (55.4 %)

 

 >5

22

12(54.5 %)

10 (45.5 %)

 

Lymph node stage

    

 negative

65

36 (55.4 %)

29 (44.6 %)

0.027

 positive

64

23 (35.9 %)

41 (64.1 %)

 

Grade

    

 G1

24

13 (54.2 %)

11 (45.8 %)

0.612

 G2

30

14 (46.7 %)

16 (53.3 %)

 

 G3

75

32 (42.7 %)

43 (57.3 %)

 

Clinical stagea

    

 I

19

11 (57.9 %)

8 (42.1 %)

0.374

 II

62

29 (46.8 %)

33 (53.2 %)

 

 III and IV

46

18 (39.1 %)

28 (60.9 %)

 

Histological type

    

 IDC

101

45 (44.6 %)

56 (55.4 %)

0.250

 ILC

18

11 (61.1 %)

7 (38.9 %)

 

 Others

10

3 (30.0 %)

7 (70.0 %)

 

Ki-67 LI

    

 Low (≤14 %)

39

17 (43.6 %)

22 (56.4 %)

0.747

 High (>14 %)

90

42 (46.7 %)

48 (53.3 %)

 

Chemotherapy

    

 AC

45

22 (48.9 %)

23 (51.1 %)

0.945

 AC-T

72

32 (44.4 %)

40 (55.6 %)

 

 Others

10

4 (40.0 %)

6 (60.0 %)

 

 None

2

1 (50.0 %)

1 (50.0 %)

 

Radiotherapy

    

 No

67

30 (44.8 %)

37 (55.2 %)

0.820

 Yes

62

29 (46.8 %)

33 (53.2 %)

 

Cohort

    

 FAHHMU

49

22 (44.9 %)

27 (55.1 %)

0.820

 DLH

45

21 (46.7 %)

24 (53.5 %)

 

 DOGH

35

16 (45.7 %)

19 (54.3 %)

 
  1. Abbreviations: LN, lymph node; IDC, invasive ductal carcinoma; ILC, invasive lobular carcinoma; Ki-67 LI, Ki-67 label index; AC, Adriamycin/Cyclophosphamide; AC-T, Adriamycin/Cyclophosphamide-Taxol; FAHHMU, The Fifth Affiliated Hospital of Harbin Medical University; DOGH, Daqing Oilfield General Hospital
  2. Note: afor the variable, data for two cases are unavailable from medical records