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Table 2 Correlation between PELP1 protein expression and clinicopathological variables in patients with TNBC

From: Prognostic significance of proline, glutamic acid, leucine rich protein 1 (PELP1) in triple-negative breast cancer: a retrospective study on 129 cases

Variables n Status of PELP1 protein expression P-value
low high
Age (years)     
 ≤50 69 31 (44.9 %) 38 (55.1 %) 0.843
 >50 60 28 (46.7 %) 32 (53.3 %)  
Tumor size (cm)a     
 ≤2 31 13 (41.9 %) 18 (58.1 %) 0.635
 >2, ≤5 74 33 (44.6 %) 41 (55.4 %)  
 >5 22 12(54.5 %) 10 (45.5 %)  
Lymph node stage     
 negative 65 36 (55.4 %) 29 (44.6 %) 0.027
 positive 64 23 (35.9 %) 41 (64.1 %)  
Grade     
 G1 24 13 (54.2 %) 11 (45.8 %) 0.612
 G2 30 14 (46.7 %) 16 (53.3 %)  
 G3 75 32 (42.7 %) 43 (57.3 %)  
Clinical stagea     
 I 19 11 (57.9 %) 8 (42.1 %) 0.374
 II 62 29 (46.8 %) 33 (53.2 %)  
 III and IV 46 18 (39.1 %) 28 (60.9 %)  
Histological type     
 IDC 101 45 (44.6 %) 56 (55.4 %) 0.250
 ILC 18 11 (61.1 %) 7 (38.9 %)  
 Others 10 3 (30.0 %) 7 (70.0 %)  
Ki-67 LI     
 Low (≤14 %) 39 17 (43.6 %) 22 (56.4 %) 0.747
 High (>14 %) 90 42 (46.7 %) 48 (53.3 %)  
Chemotherapy     
 AC 45 22 (48.9 %) 23 (51.1 %) 0.945
 AC-T 72 32 (44.4 %) 40 (55.6 %)  
 Others 10 4 (40.0 %) 6 (60.0 %)  
 None 2 1 (50.0 %) 1 (50.0 %)  
Radiotherapy     
 No 67 30 (44.8 %) 37 (55.2 %) 0.820
 Yes 62 29 (46.8 %) 33 (53.2 %)  
Cohort     
 FAHHMU 49 22 (44.9 %) 27 (55.1 %) 0.820
 DLH 45 21 (46.7 %) 24 (53.5 %)  
 DOGH 35 16 (45.7 %) 19 (54.3 %)  
  1. Abbreviations: LN, lymph node; IDC, invasive ductal carcinoma; ILC, invasive lobular carcinoma; Ki-67 LI, Ki-67 label index; AC, Adriamycin/Cyclophosphamide; AC-T, Adriamycin/Cyclophosphamide-Taxol; FAHHMU, The Fifth Affiliated Hospital of Harbin Medical University; DOGH, Daqing Oilfield General Hospital
  2. Note: afor the variable, data for two cases are unavailable from medical records