Phosphorylation of a splice variant of collapsin response mediator protein 2 in the nucleus of tumour cells links cyclin dependent kinase-5 to oncogenesis

Table 4 Quick Score = Category A + Category B (possible 0-9), number of cases with each score given in columns for each cancer type

	Quick Score (A + B)
	1	2	3	4	5	6	7	8	9	Cases
Controls	0	1	0	0	0	0	0	0	0	14
Ovarian	0	0	0	1	0	0	0	0	0	79
Kidney	0	0	1	2	0	0	0	0	0	181
Prostate	0	1	1	0	0	0	0	0	0	25
Breast	0	0	4	0	0	0	0	0	0	48
Colorectal Adenoma	0	0	0	2	0	0	0	0	0	127
Follicular Lymphoma	0	2	1	1	0	0	0	0	0	46
Diffuse Large B-Cell Lymphoma (DLBCL)	0	9	10	13	5	0	0	0	0	77

Sections were stained using the anti-pCRMP2 Ser522 and visualised using DAB chromogen. The proportion of malignant cells staining positively throughout the section (termed Category A) was assigned scores from 1–6 (1 = >0 - 5 %; 2 = 6 - 20 %; 3 = 21 - 40 %; 4 = 41 - 60 %; 5 = 61 - 80 %; 6 = 81 -100 %); the average intensity of staining in malignant cells (termed Category B) was scored as 0, 1, 2, or 3, corresponding to the presence of negative, weak, moderate, and strong brown staining, respectively. Category A and Category B values were added together to produce a quick score (range from 0, negative, to 9, strong and complete). The table provides the number of cases of each tumour type with each quick score. A tumour was considered negative when all sample cores were negative, whereas > 2 positive cores was considered a positive result

ISSN: 1471-2407