Skip to main content

Table 1 Genes analysed in the study. Genes with gradually decreasing or increasing expression along the adenoma-carcinoma sequence with predictable CpG islands were selected on the basis of Kendall (tau coefficient) rank correlation analysis (−0.5 ≤ tau coefficient ≤ 0.5)

From: DNA hypermethylation and decreased mRNA expression of MAL, PRIMA1, PTGDR and SFRP1 in colorectal adenoma and cancer

Gene symbol

Gene name

ALDH1A3

aldehyde dehydrogenase 1 family, member A3

BCL2

B-cell CLL/lymphoma 2

CDX1

caudal type homeobox 1

COL1A2

collagen, type I, alpha 2

CYP27B1

cytochrome P450, family 27, subfamily B, polypeptide 1

ENTPD5

ectonucleoside triphosphate diphosphohydrolase 5

FADS1

fatty acid desaturase 1

MAL

mal, T-cell differentiation protein

PRIMA1

proline rich membrane anchor 1

PTGDR

prostaglandin D2 receptor (DP)

PTGS2

prostaglandin-endoperoxide synthase 2

SFRP1

secreted frizzled-related protein 1

SFRP2

secreted frizzled-related protein 2

SOCS3

suppressor of cytokine signaling 3

SULF1

sulfatase 1

SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

THBS2

thrombospondin 2

TIMP1

metallopeptidase inhibitor 1