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Table 1 Genes analysed in the study. Genes with gradually decreasing or increasing expression along the adenoma-carcinoma sequence with predictable CpG islands were selected on the basis of Kendall (tau coefficient) rank correlation analysis (−0.5 ≤ tau coefficient ≤ 0.5)

From: DNA hypermethylation and decreased mRNA expression of MAL, PRIMA1, PTGDR and SFRP1 in colorectal adenoma and cancer

Gene symbol Gene name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
BCL2 B-cell CLL/lymphoma 2
CDX1 caudal type homeobox 1
COL1A2 collagen, type I, alpha 2
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
FADS1 fatty acid desaturase 1
MAL mal, T-cell differentiation protein
PRIMA1 proline rich membrane anchor 1
PTGDR prostaglandin D2 receptor (DP)
PTGS2 prostaglandin-endoperoxide synthase 2
SFRP1 secreted frizzled-related protein 1
SFRP2 secreted frizzled-related protein 2
SOCS3 suppressor of cytokine signaling 3
SULF1 sulfatase 1
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
THBS2 thrombospondin 2
TIMP1 metallopeptidase inhibitor 1