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Fig. 6 | BMC Cancer

Fig. 6

From: Inhibition of IGF1-R overcomes IGFBP7-induced chemotherapy resistance in T-ALL

Fig. 6

Apoptosis in Jurkat clone over-expressing IGFBP7 upon treatment with cytostatic drugs in combination with IGF1-R inhibition. Jurkat clones transfected with pCntrl or pIGFBP7 were incubated for one day with different drugs in combination with 500 nM IGF1-R-inhibitor AEW541. Cells stained with AnnexinV and 7‑AAD were assessed by flow cytometry. Mean values ± SEM of 4 independent experiments done in triplicates; *P-value≤ 0.05 (Mann-Whitney-U test)

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