Ipsilateral 2

First tumour
  
Likely to be de novo
 
Second tumour

2p, 3p (partial),

7q, 8q, 10p (partial), 19p

Ipsilateral 6

First tumour

3p (partial)

17q (partial)

Likely to be recurrent

The second tumour still retains the variation of the primary tumour, especially gain of 17q12 (Her2)

Second tumour

3p (partial), 4q, 8p, 9p, 10p, 11q, 13, 18

1q (partial), 12p, 14p, 17q (partial), 19p

Ipsilateral 11

First tumour
 
5q (partial), 8q (partial), 17q (partial)

Recurrent

Whole genome variation of primary and second tumour overlaid exactly

Second tumour
 
5q (partial), 8q (partial), 17q (partial)

Ipsilateral 12

First tumour

6q, 11q, 12q, 13

1q, 11p (partial), 12p, 12q (partial), 19

Likely to be recurrent

Similar overall patterns in chromosome 11, 12 and 19

Second tumour

2q (partial), 3p (partial), 4, 6q, 7q (partial), 11q, 12q, 13

1q, 11p (partial), 12p, 12q (partial), 15, 19

Contralateral 3

First tumour

6q, 11q, 18

1q, 11p, 17q (partial)

Likely to be de novo
 
Second tumour

6q, 16q, 22

1q, 16p, Xq

Contralateral 10

First tumour

3p

6p, 8q

Likely to be recurrent

Similar overall patterns, especially in chromosome 8, 21 and 22

Second tumour
 
6p, 8q

Contralateral 13

First tumour
 
3p (partial), 8q, 11q (partial)

Likely to be recurrent
 
Second tumour
 
3p (partial), 8q, 11q (partial)
