Table 3 Drug associated adverse events (≥20 %)
Adverse events CTCAE ver.3 | Any grade | ≥ Grade 3 | ||
|---|---|---|---|---|
IFN-α alone, % | Combined*, % | IFN-α alone, % | Combined*, % | |
Hand foot skin reaction | 0.0 | 64.3 | 0.0 | 21.4 |
Rash | 2.4 | 52.4 | 0.0 | 21.4 |
Malaise | 7.1 | 57.1 | 0.0 | 14.3 |
Diarrhea | 0.0 | 47.6 | 0.0 | 0.0 |
Thrombocytopenia | 2.4 | 45.2 | 0.0 | 7.1 |
Anorexia | 0.0 | 45.2 | 0.0 | 11.9 |
Leukocytopenia | 9.5 | 47.6 | 0.0 | 11.9 |
Lipase elevation | 7.1 | 31.0 | 2.4 | 7.1 |
Alopecia | 0.0 | 35.7 | 0.0 | 0.0 |
Hypertension | 0.0 | 26.2 | 0.0 | 14.3 |
Amylase elevation | 7.1 | 28.6 | 2.4 | 9.5 |
Fatigue | 0.0 | 26.2 | 0.0 | 4.8 |
Pyrexia | 54.8 | 21.4 | 0.0 | 0.0 |