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Table 3 Methylation marker concordances for selected phenotypes

From: Evaluation of an assay for methylated BCAT1 and IKZF1 in plasma for detection of colorectal neoplasia

Most advanced findings

No.

No. BCAT1/IKZF1 positive

P-value1

+/+

+/-

-/+

-/-

Cancer

129

51

23

11

44

0.059

Advanced adenoma

338

3

13

4

318

0.052

Non-neoplastic pathologies

838

9

37

6

786

<0.0001

Normal colon/rectum

450

1

21

2

426

0.0002

  1. 1McNemar t-test