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Table 3 Methylation marker concordances for selected phenotypes

From: Evaluation of an assay for methylated BCAT1 and IKZF1 in plasma for detection of colorectal neoplasia

Most advanced findings No. No. BCAT1/IKZF1 positive P-value1
+/+ +/- -/+ -/-
Cancer 129 51 23 11 44 0.059
Advanced adenoma 338 3 13 4 318 0.052
Non-neoplastic pathologies 838 9 37 6 786 <0.0001
Normal colon/rectum 450 1 21 2 426 0.0002
  1. 1McNemar t-test