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Table 1 Demographic details for all eligible volunteers

From: Evaluation of an assay for methylated BCAT1 and IKZF1 in plasma for detection of colorectal neoplasia

Principal Diagnosis   Age (years) Females Males
  N (%) \( \tilde{x}{}^4\left( min\mathit{\hbox{-}} max\right) \) N (%), \( \tilde{x} \) age N (%), \( \tilde{x} \) age
Total cases 2105 62 (33 - 90) 973 (46), 61 1132 (54), 63
No Neoplasia1 1291 (61) 61 (33 - 86) 673 (52), 60 618 (48), 61
 Normal colon 452 (21) 58 (40 - 85) 259 (57), 57 193 (43), 60
 Non-neoplastic pathology2 778 (37) 63 (40 - 86) 382 (49), 64 396 (51), 63
 IBD 61 (3) 51 (33 - 86) 32 (53), 51 29 (48), 51
Adenoma 685 (33) 64 (40 - 85) 246 (36), 63 439 (64), 64
 Non advanced 346 (17) 65 (40 - 85) 130 (38), 64 216 (62), 65
 Advanced3 339 (16) 63 (41 - 85) 116 (34), 62 223 (66), 64
Cancer 129 (6) 69 (37 - 90) 54 (42), 68 75 (58), 69
 Stage I 29 (1) 64 (45 - 86) 13 (45), 62 16 (55), 66
 Stage II 42 (2) 72 (46 - 90) 17 (41), 75 25 (60), 72
 Stage III 40 (2) 69 (39 - 88) 16 (40), 69 24 (60), 69
 Stage IV 16 (1) 66 (37 - 88) 7 (44), 67 9 (56), 65
 Unstaged 2 (0.1) 71 (57 - 85) 1 (50), 57 1 (50), 85
  1. 1All non-neoplastic cases, i.e. excluding only cases with adenomas or cancer. 2Including polyps (hyperplastic, unspecified, other polyps), angiodysplasia, haemorrhoids and diverticular disease. Excluding inflammatory bowel disease (IBD), which is shown separately. 3Includes two stage 0 (i.e. non-invasive) cancers. \( {}^4\tilde{x} \); the median value