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Table 1 Demographic details for all eligible volunteers

From: Evaluation of an assay for methylated BCAT1 and IKZF1 in plasma for detection of colorectal neoplasia

Principal Diagnosis

 

Age (years)

Females

Males

 

N (%)

\( \tilde{x}{}^4\left( min\mathit{\hbox{-}} max\right) \)

N (%), \( \tilde{x} \) age

N (%), \( \tilde{x} \) age

Total cases

2105

62 (33 - 90)

973 (46), 61

1132 (54), 63

No Neoplasia1

1291 (61)

61 (33 - 86)

673 (52), 60

618 (48), 61

 Normal colon

452 (21)

58 (40 - 85)

259 (57), 57

193 (43), 60

 Non-neoplastic pathology2

778 (37)

63 (40 - 86)

382 (49), 64

396 (51), 63

 IBD

61 (3)

51 (33 - 86)

32 (53), 51

29 (48), 51

Adenoma

685 (33)

64 (40 - 85)

246 (36), 63

439 (64), 64

 Non advanced

346 (17)

65 (40 - 85)

130 (38), 64

216 (62), 65

 Advanced3

339 (16)

63 (41 - 85)

116 (34), 62

223 (66), 64

Cancer

129 (6)

69 (37 - 90)

54 (42), 68

75 (58), 69

 Stage I

29 (1)

64 (45 - 86)

13 (45), 62

16 (55), 66

 Stage II

42 (2)

72 (46 - 90)

17 (41), 75

25 (60), 72

 Stage III

40 (2)

69 (39 - 88)

16 (40), 69

24 (60), 69

 Stage IV

16 (1)

66 (37 - 88)

7 (44), 67

9 (56), 65

 Unstaged

2 (0.1)

71 (57 - 85)

1 (50), 57

1 (50), 85

  1. 1All non-neoplastic cases, i.e. excluding only cases with adenomas or cancer. 2Including polyps (hyperplastic, unspecified, other polyps), angiodysplasia, haemorrhoids and diverticular disease. Excluding inflammatory bowel disease (IBD), which is shown separately. 3Includes two stage 0 (i.e. non-invasive) cancers. \( {}^4\tilde{x} \); the median value