Upregulation of MicroRNA-19b predicts good prognosis in patients with hepatocellular carcinoma presenting with vascular invasion or multifocal disease

Table 3 Potential targets of miR-19b

	Expression change after miR-19b knockdown	Functions	Reference
NDRG1	Down regulated	Metastatic suppressor	[38]
EPCAM	Up regulated	Cancer cell stemness	[38–41]
HIF1A	Up regulated	Angiogenesis; Proliferation	[43, 44]
HMGB2	Up regulated	Proliferation; Predict survival of HCC	[45]
MAPK14	Up regulated	Drug resistance	[42]

NDRG1 N-myc downstream regulated gene 1, EPCAM epithelial cell adhesion molecule, HIF1A hypoxia inducible factor 1, alpha subunit, HMGB2 high mobility group box 2, MAPK14 mitogen-activated protein kinase 14

ISSN: 1471-2407