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Table 2 Multivariate analysis of the associations of disease-free survival and overall survival with various clinicopathologic parameters and miR-19b expression in patients with HCC presented with vascular invasion or multifocal diseases

From: Upregulation of MicroRNA-19b predicts good prognosis in patients with hepatocellular carcinoma presenting with vascular invasion or multifocal disease

  Disease-free survival Overall survival
Clinicopathological parameters HR 95 % CI P value HR 95 % CI P value
Age 0.947 0.517–1.737 0.861 0.527 0.204–1.357 0.184
Gender 0.857 0.440–1.672 0.568 2.184 0.726–6.569 0.165
AFP level 2.133 1.155–4.616 0.016 1.823 0.705–4.714 0.215
Tumor number 1.213 0.626–2.349 0.567 1.099 0.401–3.105 0.855
Vascular invasion 0.82 0.414–1.623 0.568 2.963 0.672–13.060 0.151
TNM stage 2.364 1.211–4.616 0.012 3.084 1.201–7.92 0.019
Tumor differentiation 1.481 0.647–3.258 0.328 3.03 1.011–9.083 0.048
miR-19b expression 0.455 0.245–0.845 0.013 0.318 0.120–0.846 0.022
Liver cirrhosis 0.897 0.486–1.656 0.728 0.904 0.349–2.339 0.835
  1. miR-19b microRNA-19b, HR hazard ratio, CI confidence interval, AFP α-fetoprotein