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Table 1 Correlation of miR-19b expression with clinicopathological features of hepatocellular carcinoma

From: Upregulation of MicroRNA-19b predicts good prognosis in patients with hepatocellular carcinoma presenting with vascular invasion or multifocal disease

  

miR-19b expression

Clinicopathological variables

Number of cases

High

Low

P

Age

 > 60

33(40.7)

16(40)

17(41.5)

0.893

 < 60

48(59.3)

24(60)

24(58.5)

 

Gender

 Male

55(67.9)

25(62.5)

30(73.2)

0.304

 Female

26(32.1)

15(37.5)

11(26.8)

 

TNM stage

 II

58(71.6)

31(77.5)

27(65.9)

0.245

 III + IV

23(28.4)

9(22.5)

14(34.1)

 

Liver cirrhosis

 Yes

26(32.1)

15(37.5)

11(26.8)

0.304

 No

55(67.9)

25(62.5)

30(73.2)

 

Vascular invasiona

 Presence

62(76.5)

29(72.5)

33(80.5)

0.369

 Absence

19(23.5)

11(27.5)

8(19.5)

 

AFP (ng/ml)

 > 20

48(59.3)

29(72.5)

19(46.3)

0.017

 < 20

33(40.7)

11(27.5)

22(53.7)

 

Tumor differentiation

 W + M

66(81.5)

32(80)

34(82.9)

0.735

 P

15(18.5)

8(20)

7(17.1)

 

Tumor number

 Solitary

58(71.6)

30(75)

28(68.3)

0.503

 Multiple

23(28.4)

10(25)

13(31.7)

 
  1. AFP, α-fetoprotein, W well differentiated, M moderate differentiated, P Poorly differentiated, BCLC Barcelona Clinic Liver Cancer
  2. aPresence of vascular invasion represented BCLC stage C; absence of vascular invasion represented BCLC stage B