Fig. 1

a MiRNAs are deregulated in hepatocellular carcinoma as detected by miRNA microarray. Five pairs of hepatocellular carcinoma and adjacent non-tumor liver tissue matches were analyzed using SurePrint G3 ChIP/CH3 1X1M array (Agilent Technologies, Santa Clara, CA, USA). Rows: miRNAs; columns: cases. For each miRNA, red represents higher expression and green represents lower expression than the corresponding adjacent non-tumoral liver tissue expression. S1, sample 1; S2, sample 2; S3, sample 3; S4, sample 4; S5, sample 5. b MiR-19b is overexpressed in the HCC tissues compared with normal adjacent liver tissue (median expression level 0.3246, range 0.0169 to 6.667, P < 0.001, Mann–Whitney test). miR-19b, microRNA-19b. HCC, hepatocellular carcinoma