Fig. 8
From: Regulation of IL-8 gene expression in gliomas by microRNA miR-93
a Proposed model for the control of the changes of IL-8 and miR-93 expression during the transition from normal brain tissues to LGG and to HGG. In the scheme is also indicated some effects (namely of VEGF, MCP-1, PDGF-B) associated to miR-93 down-regulation during LGG to HGG transition. b Proposed inhibitory effects of miR-93 within the microenvironment participating to glioma angiogenesis [59]