Table 4 Univariate and multivariate Cox proportional analysis regarding disease-free-survival

<65

1 (referent)

0.362

1 (referent)

0.370

≥65

1.47 (0.64-3.37)

1.69(0.54-5.31)

Female

1 (referent)

0.436

1 (referent)

0.643

Male

0.85(0.56-1.29)

0.89(0.54-1.46)

0 ~ 1

1 (referent)

0.001

1 (referent)

0.596

≥2

1.81(1.15-2.85)

1.16(0.68-1.97)

No

1 (referent)

0.02

1 (referent)

0.575

Yes

5.51(1.31-23.09)

0.66(0.16-2.78)

No

1 (referent)

0.510

1 (referent)

0.247

Yes

0.68(0.21-2.15)

2.52(0.53-12.06)

No

1 (referent)

0.470

1 (referent)

0.064

Yes

1.23 (0.70-2.19)

1.95(0.96-3.96)

Superficial

1 (referent)

<0.001

1 (referent)

0.002

Deep

4.07 (2.39-6.93)

2.841.47-5.49)

G1

1 (referent)

0.003

NA

NA

G2

2.54 (1.37-4.71)

<0.001

G3

6.71(3.43-13.12)

<5 cm

1 (referent)

<0.001

NA

NA

≥5 cm

2.22(1.43-3.45)

Trunk&extremity

1 (referent)

<0.001

1 (referent)

0.132

head/neck&intra-abdominal

2.26 (1.48-3.46)

1.49(0.89-2.52)

IA + IB

1 (referent)

0.001

1 (referent)

0.002

IIA + IIB

2.72(1.51-4.89)

<0.001

1.85(0.98-3.50)

0.057

III + IV

5.37(2.72-10.61)

3.60(1.74-7.46)

Yes

1 (referent)

0.216

1 (referent)

0.560

No

1.31(0.85-2.03)

1.17(0.70-1.95)

Adjuvant chemocherapy

Yes

1 (referent)

0.316

1 (referent)

0.753

No

1.30(0.78-2.19)

1.10(0.61-1.97)

<133.915

1 (referent)

0.011

1 (referent)

0.032

≥133.915

1.75(1.14-2.70)

1.77(1.05-2.97)

<2.5

1 (referent)

0.018

1 (referent)

0.516

≥2.5

1.71(1.10-2.66)

0.83(0.48-1.44)