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Table 3 Methylation frequency (%) comparison of SFRP CpG sites in three tissue groups

From: Secreted frizzled-related protein promotors are hypermethylated in cutaneous squamous carcinoma compared with normal epidermis

Genes

No. of CpG islands

Frequency of promoter methylation (%)

T vs. N

T vs. A

A vs. N

SFRP1

17

82.35 (14/17)

58.82 (10/17)

29.41 (5/17)

SFRP2

14

50 (7/14)

57.14 (8/14)

42.86 (6/14)

SFRP4

18

72.22 (13/18)

72.22 (13/18)

61.11 (11/18)

SFRP5

11

54.54 (6/11)

54.54 (6/11)

54.54 (6/11)

P*-value

 

<0.05

<0.05

<0.05

  1. T tumor tissues; A adjacent tissues; N normal samples
  2. *Nonparametric Mann-Whitney U test