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Fig. 7 | BMC Cancer

Fig. 7

From: The Deleted in Liver Cancer 1 (Dlc1) tumor suppressor is haploinsufficient for mammary gland development and epithelial cell polarity

Fig. 7

Luminal filling of the acinar structures formed from mammary epithelial cells of Dlc1gt/+ mice grown in 3D Matrigel culture is not due to defects in apoptosis. Representative images of acinar structures from mammary epithelial cells from 10 week old wild type mice (a & e) at days 6 & 12 after culturing in Matrigel or treated with etoposide (b & f) and stained with cleaved caspase-3 antibody and To-Pro-3. Acinar structures of mammary epithelial cells from Dlc1gt/+ mice at day 6 (c) and day 12 (g) or treated with etoposide (d & h). Scale bar 100 μm

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