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Table 2 pCR prediction scores and their relationship with pCR

From: ER, PgR, Ki67, p27Kip1, and histological grade as predictors of pathological complete response in patients with HER2-positive breast cancer receiving neoadjuvant chemotherapy using taxanes followed by fluorouracil, epirubicin, and cyclophosphamide concomitant with trastuzumab

Scores pCR Non-pCR pCR rate (%) p-value
0 0 4 -  
1 2 5 28.6  
2 8 9 47.1  
3 11 12 47.8  
4 20 7 74.1  
5 43 8 84.3 0.0001*
  1. One point each was assigned for high HG, ER negative, PgR negative, high Ki-67 LI, and low p27Kip1 expression
  2. pCR, pathological complete response
  3. *p < 0.05 was considered significant; significant values are shown in bold