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Table 2 pCR prediction scores and their relationship with pCR

From: ER, PgR, Ki67, p27Kip1, and histological grade as predictors of pathological complete response in patients with HER2-positive breast cancer receiving neoadjuvant chemotherapy using taxanes followed by fluorouracil, epirubicin, and cyclophosphamide concomitant with trastuzumab

Scores

pCR

Non-pCR

pCR rate (%)

p-value

0

0

4

-

 

1

2

5

28.6

 

2

8

9

47.1

 

3

11

12

47.8

 

4

20

7

74.1

 

5

43

8

84.3

0.0001*

  1. One point each was assigned for high HG, ER negative, PgR negative, high Ki-67 LI, and low p27Kip1 expression
  2. pCR, pathological complete response
  3. *p < 0.05 was considered significant; significant values are shown in bold
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BMC Cancer

ISSN: 1471-2407

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