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Table 6 Univariate analysis with clinicopathological features in GC

From: Mitogen-activated protein kinase activator with WD40 repeats (MAWD) and MAWD-binding protein induce cell differentiation in gastric cancer

Features MAWBP expression (%) MAWD expression (%) TGF-beta expression (%) E-cadherin expression (%) PGC expression (%)
Sex      
Male 37/151(24.5) 44/146(30.1) 69/149(46.3) 60/143(41.9) 54/152(35.5)
Female 22/71(30.9) 25/68(36.8) 29/65(44.6) 35/64(54.6) 36/72(50.0)
P-value 0.195 0.209 0.469 0.061 0.028
Age at diagnosis      
<60 24/91(26.3) 36/89(40.4) 41/88(46.6) 38/83(45.8) 36/91(38.8)
≥60 35/128(27.3) 31/121(29.2) 55/122(45.1) 54/121(44.6) 52/129(38.9)
P-value 0.500 0.017 0.469 0.492 0.512
TNM stage      
I 12/20(60.0) 9/20(45.0) 11/20(55.0) 11/20(50.0) 10/21(47.6)
II 18/78(17.2) 24/75(32.0) 31/75(41.3) 28/72(38.9) 32/78(41.0)
III 11/64(17.2) 14/60(23.3) 27/61(44.3) 32/61(52.5) 29/65(44.6)
IV 18/54(33.3) 21/52(40.3) 27/51(52.9) 21/48(43.8) 17/53(32.1)
P-value 0.001 0.160 0.501 0.355 0.481
Tumor depth      
T1-T2 16/45(36) 19/46(41.3) 25/45(55.6) 17/42(40.5) 18/47(38.3)
T3-T4 43/173(24.9) 49/163(30.1) 72/164(43.9) 75/161(46.6) 70/172(40.7)
P-value 0.107 0.105 0.111 0.298 0.451
Lymph node status      
N0 21/52(40.4) 20/52(38.5) 27/51(52.9) 24/47(51.1) 23/54(42.6)
N1 18/77(23.4) 24/74(32.4) 32/73(43.8) 29/77(37.7) 36/78(46.2)
N3 12/68(17.6) 18/62(29.0) 29/66(43.9) 31/62(50.0) 23/66(34.8)
N4 8/19(42.1) 6/19(31.6) 9/17(52.9) 8/15(53.3) 6/19(31.6)
P-value 0.016 0.760 0.681 0.339 0.452
Distant metastasis      
M0 51/190(26.8) 56/183(30.6) 81/182(44.5) 82/179(45.8) 78/192(40.6)
M1 8/28(28.6) 12/26(46.2) 16/27(59.3) 10/24(41.7) 10/27(37.0)
P-value 0.504 0.089 0.110 0.437 0.446
Differentiation      
D1 6/12(50.0) 4/11(36.3) 9/12(75.0) 8/12(66.7) 1/13(7.6)
D2 30/78(38.5) 28/76(36.8) 41/74(55.4) 36/71(50.7) 32/79(40.5)
D3 22/123(17.9) 35/120(29.2) 45/120(37.5) 47/116(40.5) 52/125(41.6)
P-value 0.031 0.649 0.006 0.046 0.035