Fig. 2

Cisplatin-surviving NSCLC clones have heterogeneous gene expression patterns. Global transcriptome analysis was performed on RNA extracted from cisplatin-surviving (1 h, 10 μM) versus untreated NSCLC clones. Fold changes in the expression (relative to untreated sample) of the top 10 up- and down-regulated genes from each biological replicate are depicted separately; replicate 1 (upper panel), replicate 2 (middle panel), replicate 3 (lower panel). Stars mark candidate genes that were subsequently validated by q-RT-PCR