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Table 2 Univariate and multivariate analyses of different prognostic parameters for overall survival of 152 glioblastoma patients

From: Pre-treatment neutrophil-to-lymphocyte ratio is associated with neutrophil and T-cell infiltration and predicts clinical outcome in patients with glioblastoma

Variable

Univariate

Multivariate

P

HR

95 % CI

P

HR

95 % CI

Sexa

0.704

0.930

0.641–1.351

-

-

-

Ageb

0.050

1.013

1.000–1.026

0.157

1.010

0.996–1.024

Tumor sizeb

0.559

0.998

0.991–1.005

-

-

-

KPSb

0.034

0.986

0.973–0.999

0.023

0.985

0.972–0.998

Resectiona

0.047

0.800

0.641–0.997

0.183

0.860

0.688–1.074

BMIb

0.206

1.033

0.982–1.086

-

-

-

MGMT promotera

0.011

0.605

0.411–0.890

0.041

0.659

0.442–0.984

Pretreatment PLRb

0.013

1.004

1.001–1.007

0.152

1.003

0.999–1.007

Postoperative NLRb

0.285

1.015

0.988–1.043

-

-

-

Pretreatment neutrophilsb

0.620

1.010

0.971–1.051

-

-

-

Pretreatment lymphocytesb

0.531

0.999

0.996–1.002

-

-

-

Pretreatment plateletsb

0.637

0.999

0.997–1.002

-

-

-

Pretreatment NLRb

<0.001

1.078

1.038–1.119

0.037

1.050

1.003–1.100

  1. BMI Body Mass Index, KPS Karnofsky Performance Scores, MGMT O(6)-methylguanine-DNA-methyltransferase, NLR Neutrophil to Lymphocyte Ratio, PLR Platelet to Lymphocyte Ratio
  2. acategorical variable; bcontinuous variable