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Fig. 5 | BMC Cancer

Fig. 5

From: Effects of cytochalasin congeners, microtubule-directed agents, and doxorubicin alone or in combination against human ovarian carcinoma cell lines in vitro

Fig. 5

Effects of cytochalasin congeners and verapamil on RNA expression of ATP binding cassette proteins and the efflux of rhodamine 123 in SK human ovarian carcinoma cell lines. a Relative RNA expression of ABCB1 (P-gp), ABCC1 (MRP1), and ABCC2 (MRP2) in SK human ovarian carcinoma cell lines prior to and after treatment with cytochlalasins as assessed by RT-PCR. Primer sequences used in the reaction are shown in TableĀ 1. b Cells were treated with the indicated agents, and then exposed to Rh123. c Cells were incubated with Rh123, and then placed in fresh medium. The concentrations of each agent used are indicated in the individual panels. Bars represent SEM for each treatment group

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