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Fig. 4 | BMC Cancer

Fig. 4

From: Neoadjuvant administration of Semliki Forest virus expressing interleukin-12 combined with attenuated Salmonella eradicates breast cancer metastasis and achieves long-term survival in immunocompetent mice

Fig. 4

Antitumor effect of LVR01 in 4T1 tumor bearing and tumor-excised animals. a Schematic representation of the therapeutic protocol performed in this study. Two doses of LVR01 (2×107 cfu in 50 μl PBS) or 50 μl PBS were i.t. injected at days 10 and 13 after 4T1 cells inoculation. In the indicated groups, the treated tumors were surgically removed at day 16 (S-16). b Kaplan–Meier plot shows the survival rate of treated and control mice (n = 5-9). Non-significant (n.s); p< 0.001 (***)

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BMC Cancer

ISSN: 1471-2407

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