Table 2 Toxicity (n = 31)
| Â | Number of patients, n (%) | |||||
|---|---|---|---|---|---|---|
| Â | Grade 1 | Grade 2 | Grade 3 | Grade 4 | All grades | Grade 3/4 |
Hematological adverse events | ||||||
 Anemia | 4 | 4 | 2 | 0 | 10 (32) | 2 (6) |
 Thrombocytopenia | 7 | 1 | 0 | 0 | 8 (26) | 0 (0) |
 Neutropenia | 4 | 1 | 1 | 0 | 6 (19) | 1 (3) |
 Febrile neutropenia | – | – | 1 | 0 | 1 (3) | 1 (3) |
Non-hematological adverse events | ||||||
 Stomatitis | 7 | 8 | 8 | 0 | 23 (74) | 8 (26) |
 Fatigue | 13 | 10 | 0 | – | 23 (74) | 0 (0) |
 Anorexia | 10 | 9 | 2 | 0 | 21 (68) | 2 (6) |
 Diarrhea | 8 | 4 | 3 | 0 | 15 (48) | 3 (10) |
 Skin pigmentation | 8 | 4 | 0 | 0 | 12 (39) | 0 (0) |
 Hypertension | 7 | 2 | 1 | 0 | 10 (32) | 1 (3) |
 Nausea | 8 | 1 | 0 | – | 9 (29) | 0 (0) |
 Epistaxis | 9 | 0 | 0 | 0 | 9 (29) | 0 (0) |
 Watering eyes | 4 | 1 | 0 | – | 5 (16) | 0 (0) |
 Vomiting | 3 | 1 | 0 | 0 | 4 (13) | 0 (0) |